Unraveling the causes of adaptive benefits of synonymous mutations in TEM-1 β-lactamase

While synonymous mutations were long thought to be without phenotypic consequences, there is growing evidence they can affect gene expression, protein folding, and ultimately the fitness of an organism. In only a few cases have the mechanisms by which synonymous mutations affect the phenotype been e...

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Detalles Bibliográficos
Autores principales: Zwart, Mark P., Schenk, Martijn F., Hwang, Sungmin, Koopmanschap, Bertha, de Lange, Niek, van de Pol, Lion, Nga, Tran Thi Thuy, Szendro, Ivan G., Krug, Joachim, de Visser, J. Arjan G. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6180035/
https://www.ncbi.nlm.nih.gov/pubmed/29967397
http://dx.doi.org/10.1038/s41437-018-0104-z

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