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Myocardin regulates mitochondrial calcium homeostasis and prevents permeability transition

Myocardin is a transcriptional co-activator required for cardiovascular development, but also promotes cardiomyocyte survival through an unclear molecular mechanism. Mitochondrial permeability transition is implicated in necrosis, while pore closure is required for mitochondrial maturation during ca...

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Detalles Bibliográficos
Autores principales: Mughal, Wajihah, Martens, Matthew, Field, Jared, Chapman, Donald, Huang, Jianhe, Rattan, Sunil, Hai, Yan, Cheung, Kyle G., Kereliuk, Stephanie, West, Adrian R., Cole, Laura K., Hatch, Grant M., Diehl-Jones, William, Keijzer, Richard, Dolinsky, Vernon W., Dixon, Ian M., Parmacek, Michael S., Gordon, Joseph W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6180099/
https://www.ncbi.nlm.nih.gov/pubmed/29511336
http://dx.doi.org/10.1038/s41418-018-0073-z