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Myocardin regulates mitochondrial calcium homeostasis and prevents permeability transition
Myocardin is a transcriptional co-activator required for cardiovascular development, but also promotes cardiomyocyte survival through an unclear molecular mechanism. Mitochondrial permeability transition is implicated in necrosis, while pore closure is required for mitochondrial maturation during ca...
Autores principales: | Mughal, Wajihah, Martens, Matthew, Field, Jared, Chapman, Donald, Huang, Jianhe, Rattan, Sunil, Hai, Yan, Cheung, Kyle G., Kereliuk, Stephanie, West, Adrian R., Cole, Laura K., Hatch, Grant M., Diehl-Jones, William, Keijzer, Richard, Dolinsky, Vernon W., Dixon, Ian M., Parmacek, Michael S., Gordon, Joseph W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6180099/ https://www.ncbi.nlm.nih.gov/pubmed/29511336 http://dx.doi.org/10.1038/s41418-018-0073-z |
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