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Bordetella bronchiseptica Colonization Limits Efficacy, but Not Immunogenicity, of Live-Attenuated Influenza Virus Vaccine and Enhances Pathogenesis After Influenza Challenge

Intranasally administered live-attenuated influenza virus (LAIV) vaccines provide significant protection against heterologous influenza A virus (IAV) challenge. However, LAIV administration can modify the bacterial microbiota in the upper respiratory tract, including alterations in species that caus...

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Detalles Bibliográficos
Autores principales: Hughes, Holly R., Brockmeier, Susan L., Loving, Crystal L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6180198/
https://www.ncbi.nlm.nih.gov/pubmed/30337924
http://dx.doi.org/10.3389/fimmu.2018.02255

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