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Identification of a Shared Cytochrome p4502E1 Epitope Found in Anesthetic Drug-Induced and Viral Hepatitis

Cytochrome p4502E1 (CYP2E1) autoantibodies are biomarkers for drug-induced hepatitis and chronic hepatitis C. However, major histocompatibility-restricted CYP2E1 epitopes associated with these diseases have not been identified. We hypothesized that CYP2E1 epitopes associated with different types of...

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Detalles Bibliográficos
Autores principales: McCarthy, Elisa K., Vakos, Amanda, Cottagiri, Merylin, Mantila, Joel J., Santhanam, Lakshmi, Thomas, David L., Amzel, L. Mario, Rose, Noel R., Njoku, Dolores B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6180222/
https://www.ncbi.nlm.nih.gov/pubmed/30305319
http://dx.doi.org/10.1128/mSphere.00453-18