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Structure of the Recombinant Neisseria gonorrhoeae Adhesin Complex Protein (rNg-ACP) and Generation of Murine Antibodies with Bactericidal Activity against Gonococci

Neisseria gonorrhoeae (gonococcus [Ng]) is the causative organism of the sexually transmitted disease gonorrhoea, and no effective vaccine exists currently. In this study, the structure, biological properties, and vaccine potential of the Ng-adhesin complex protein (Ng-ACP) are presented. The crysta...

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Detalles Bibliográficos
Autores principales: Almonacid-Mendoza, Hannia Liliana, Humbert, María Victoria, Dijokaite, Aiste, Cleary, David W., Soo, Yiwen, Hung, Miao-Chiu, Orr, Christian M., Machelett, Moritz M., Tews, Ivo, Christodoulides, Myron
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6180225/
https://www.ncbi.nlm.nih.gov/pubmed/30305317
http://dx.doi.org/10.1128/mSphere.00331-18