Cargando…

Stress signaling in breast cancer cells induces matrix components that promote chemoresistant metastasis

Metastatic progression remains a major burden for cancer patients and is associated with eventual resistance to prevailing therapies such as chemotherapy. Here, we reveal how chemotherapy induces an extracellular matrix (ECM), wound healing, and stem cell network in cancer cells via the c‐Jun N‐term...

Descripción completa

Detalles Bibliográficos
Autores principales:	Insua‐Rodríguez, Jacob, Pein, Maren, Hongu, Tsunaki, Meier, Jasmin, Descot, Arnaud, Lowy, Camille M, De Braekeleer, Etienne, Sinn, Hans‐Peter, Spaich, Saskia, Sütterlin, Marc, Schneeweiss, Andreas, Oskarsson, Thordur
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2018
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6180299/ https://www.ncbi.nlm.nih.gov/pubmed/30190333 http://dx.doi.org/10.15252/emmm.201809003

Ejemplares similares

Metastasis-initiating cells induce and exploit a fibroblast niche to fuel malignant colonization of the lungs
por: Pein, Maren, et al.
Publicado: (2020)

Perivascular tenascin C triggers sequential activation of macrophages and endothelial cells to generate a pro-metastatic vascular niche in the lungs
por: Hongu, Tsunaki, et al.
Publicado: (2022)

Tenascin C in metastasis: A view from the invasive front
por: Lowy, Camille M, et al.
Publicado: (2015)

Myasthenia Gravis in Pregnancy: A Case Report
por: Berlit, Sebastian, et al.
Publicado: (2012)

The hysterectomy: influence of the surgical method in benign disease on convalescence and quality of life
por: Spaich, Saskia, et al.
Publicado: (2022)

Patient Preferences Regarding Chemotherapy in Metastatic Breast Cancer—A Conjoint Analysis for Common Taxanes
por: Spaich, Saskia, et al.
Publicado: (2018)

Stress-induced metastatic niches in breast cancer
por: Oskarsson, Thordur
Publicado: (2020)

First experiences with a diode laser in major gynecological laparoscopic procedures show lack of benefit and impaired feasibility
por: Spaich, Saskia, et al.
Publicado: (2023)

Prevalence of higher-grade dysplasia in persistently high-risk human papillomavirus positive, cytology negative women after introduction of the new cervical cancer screening in Germany
por: Berger, Laura, et al.
Publicado: (2023)

Pathological functions of the small GTPase Arf6 in cancer progression: Tumor angiogenesis and metastasis
por: Hongu, Tsunaki, et al.
Publicado: (2016)

Frequent Molecular Subtype Switching and Gene Expression Alterations in Lung and Pleural Metastasis From Luminal A–Type Breast Cancer
por: Klebe, Max, et al.
Publicado: (2020)

Activation of the Small G Protein Arf6 by Dynamin2 through Guanine Nucleotide Exchange Factors in Endocytosis
por: Okada, Risa, et al.
Publicado: (2015)

Arf6 in lymphatic endothelial cells regulates lymphangiogenesis by controlling directional cell migration
por: Lin, Yueh-Chien, et al.
Publicado: (2017)

Longitudinal cosmetic outcome after planned IORT boost with low kV X-rays—monocentric results from the TARGIT BQR registry
por: Goerdt, Lukas, et al.
Publicado: (2023)

Epithelial Protein Lost in Neoplasm α (Eplin-α) is transcriptionally regulated by G-actin and MAL/MRTF coactivators
por: Leitner, Laura, et al.
Publicado: (2010)

Matrix Metalloproteinases in Chemoresistance: Regulatory Roles, Molecular Interactions, and Potential Inhibitors
por: Tune, Bernadette Xin Jie, et al.
Publicado: (2022)

Molecular Subtype Conversion between Primary and Metastatic Breast Cancer Corresponding to the Dynamics of Apoptotic and Intact Circulating Tumor Cells
por: Stefanovic, Stefan, et al.
Publicado: (2019)

Assessment of Arf6 Deletion in PLB-985 Differentiated in Neutrophil-Like Cells and in Mouse Neutrophils: Impact on Adhesion and Migration
por: Gamara, Jouda, et al.
Publicado: (2020)

Using Bacterial Artificial Chromosomes in Leukemia Research: The Experience at the University Cytogenetics Laboratory in Brest, France
por: De Braekeleer, Etienne, et al.
Publicado: (2011)

Impact of mRNA-Assessed Molecular Subtype Conversion, Intact and Apoptotic Circulating Tumor Cells on Survival of Metastatic Breast Cancer Patients: Proof of Principle
por: Stefanovic, Stefan, et al.
Publicado: (2020)

Phenotypic Basis for Matrix Stiffness-Dependent Chemoresistance of Breast Cancer Cells to Doxorubicin
por: Joyce, M. Hunter, et al.
Publicado: (2018)

PB1715: UNLEASHING NATURAL KILLER (NK) CELLS TO PROMOTE ANTI-LEUKEMIC IMMUNITY
por: Tsoukala, Ioanna, et al.
Publicado: (2023)

Matrix stiffness induces epithelial–mesenchymal transition and promotes chemoresistance in pancreatic cancer cells
por: Rice, A J, et al.
Publicado: (2017)

Phospholipase D1 facilitates second-phase myoblast fusion and skeletal muscle regeneration
por: Teng, Shuzhi, et al.
Publicado: (2015)

Physiological function of phospholipase D2 in anti-tumor immunity: regulation of CD8(+) T lymphocyte proliferation
por: Ngo Thai Bich, Van, et al.
Publicado: (2018)

The Lack of Evidence for an Association between Cancer Biomarker Conversion Patterns and CTC-Status in Patients with Metastatic Breast Cancer
por: Stefanovic, Stefan, et al.
Publicado: (2020)

Development of a Taste-Masked Orodispersible Film Containing Dimenhydrinate
por: Preis, Maren, et al.
Publicado: (2012)

The small G protein Arf6 expressed in keratinocytes by HGF stimulation is a regulator for skin wound healing
por: Miura, Yuki, et al.
Publicado: (2017)

Arf6 exacerbates allergic asthma through cell-to-cell transmission of ASC inflammasomes
por: Lee, SangJoon, et al.
Publicado: (2021)

Programming .NET components
por: Lowy, Juval
Publicado: (2005)

Extracellular Matrix Proteins Expression Profiling in Chemoresistant Variants of the A2780 Ovarian Cancer Cell Line
por: Januchowski, Radosław, et al.
Publicado: (2014)

COM and .NET Component services
por: Lowy, Juval
Publicado: (2001)

Fluorescence in situ hybridization testing of chromosomes 6, 8, 9 and 11 in melanocytic tumors is difficult to automate and reveals tumor heterogeneity in melanomas
por: Uguen, Arnaud, et al.
Publicado: (2016)

The power of the 2x2 matrix: using 2x2 thinking to solve business problems and make better decisions
por: Lowy, Alex, et al.
Publicado: (2004)

The sialyl-glycolipid stage-specific embryonic antigen 4 marks a subpopulation of chemotherapy-resistant breast cancer cells with mesenchymal features
por: Aloia, Andrea, et al.
Publicado: (2015)

Electrotactile Communication via Matrix Electrode Placed on the Torso Using Fast Calibration, and Static vs. Dynamic Encoding
por: Malešević, Jovana, et al.
Publicado: (2022)

Mechanisms of Matrix-Induced Chemoresistance of Breast Cancer Cells—Deciphering Novel Potential Targets for a Cell Sensitization
por: Jakubzig, Bastian, et al.
Publicado: (2018)

JAKs and STATs in chemoresistance
por: Costa-Pereira, Ana P
Publicado: (2010)

Cancer chemoresistance and BAK
por: Fox, Joanna L.
Publicado: (2015)

Chemoresistance in Pancreatic Cancer
por: Zeng, Siyuan, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_rq8i7u7g3vi58lt76a6rbndoa0