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Existing capacity for renal replacement therapy and site-specific practices for managing acute kidney injury at centers participating in the BaSICS trial

OBJECTIVE: To investigate the existing capacity for renal replacement therapy and site-specific practices for managing acute kidney injury at centers participating in the BaSICS trial. METHODS: A questionnaire was provided to the chairs of 61 intensive care units enrolled in a randomized clinical tr...

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Autores principales: Zampieri, Fernando Godinho, Araújo, Flavio, Santos, Renato Hideo Nakagawa, Cavalcanti, Alexandre Biasi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Associação de Medicina Intensiva Brasileira - AMIB 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6180470/
https://www.ncbi.nlm.nih.gov/pubmed/30328984
http://dx.doi.org/10.5935/0103-507X.20180058
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author Zampieri, Fernando Godinho
Araújo, Flavio
Santos, Renato Hideo Nakagawa
Cavalcanti, Alexandre Biasi
author_facet Zampieri, Fernando Godinho
Araújo, Flavio
Santos, Renato Hideo Nakagawa
Cavalcanti, Alexandre Biasi
author_sort Zampieri, Fernando Godinho
collection PubMed
description OBJECTIVE: To investigate the existing capacity for renal replacement therapy and site-specific practices for managing acute kidney injury at centers participating in the BaSICS trial. METHODS: A questionnaire was provided to the chairs of 61 intensive care units enrolled in a randomized clinical trial in Brazil. A total of 124 physicians completed the questionnaire. RESULTS: Approximately 15% of the patients admitted to the analyzed intensive care units received renal replacement therapy at the time of data collection. At least one renal replacement method was available in all of the analyzed units. Continuous methods were available more frequently at the private units than at the public units. The time from indication to onset of treatment was longer at the public units than at private units. The main obstacles to treatment initiation at public intensive care units were related to the availability of equipment and personnel, while the main bottleneck at private units was the nephrologist assessment. A considerable proportion of the participants stated that they would change their approach to renal replacement therapy if there were no limitations on the availability of methods in their units. CONCLUSION: There was wide variation in the availability of resources for renal replacement therapy and in the management of acute kidney injury in Brazilian intensive care units. This information should be taken into account when planning clinical trials focused on this topic in Brazil.
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spelling pubmed-61804702018-10-15 Existing capacity for renal replacement therapy and site-specific practices for managing acute kidney injury at centers participating in the BaSICS trial Zampieri, Fernando Godinho Araújo, Flavio Santos, Renato Hideo Nakagawa Cavalcanti, Alexandre Biasi Rev Bras Ter Intensiva Original Article OBJECTIVE: To investigate the existing capacity for renal replacement therapy and site-specific practices for managing acute kidney injury at centers participating in the BaSICS trial. METHODS: A questionnaire was provided to the chairs of 61 intensive care units enrolled in a randomized clinical trial in Brazil. A total of 124 physicians completed the questionnaire. RESULTS: Approximately 15% of the patients admitted to the analyzed intensive care units received renal replacement therapy at the time of data collection. At least one renal replacement method was available in all of the analyzed units. Continuous methods were available more frequently at the private units than at the public units. The time from indication to onset of treatment was longer at the public units than at private units. The main obstacles to treatment initiation at public intensive care units were related to the availability of equipment and personnel, while the main bottleneck at private units was the nephrologist assessment. A considerable proportion of the participants stated that they would change their approach to renal replacement therapy if there were no limitations on the availability of methods in their units. CONCLUSION: There was wide variation in the availability of resources for renal replacement therapy and in the management of acute kidney injury in Brazilian intensive care units. This information should be taken into account when planning clinical trials focused on this topic in Brazil. Associação de Medicina Intensiva Brasileira - AMIB 2018 /pmc/articles/PMC6180470/ /pubmed/30328984 http://dx.doi.org/10.5935/0103-507X.20180058 Text en http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Zampieri, Fernando Godinho
Araújo, Flavio
Santos, Renato Hideo Nakagawa
Cavalcanti, Alexandre Biasi
Existing capacity for renal replacement therapy and site-specific practices for managing acute kidney injury at centers participating in the BaSICS trial
title Existing capacity for renal replacement therapy and site-specific practices for managing acute kidney injury at centers participating in the BaSICS trial
title_full Existing capacity for renal replacement therapy and site-specific practices for managing acute kidney injury at centers participating in the BaSICS trial
title_fullStr Existing capacity for renal replacement therapy and site-specific practices for managing acute kidney injury at centers participating in the BaSICS trial
title_full_unstemmed Existing capacity for renal replacement therapy and site-specific practices for managing acute kidney injury at centers participating in the BaSICS trial
title_short Existing capacity for renal replacement therapy and site-specific practices for managing acute kidney injury at centers participating in the BaSICS trial
title_sort existing capacity for renal replacement therapy and site-specific practices for managing acute kidney injury at centers participating in the basics trial
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6180470/
https://www.ncbi.nlm.nih.gov/pubmed/30328984
http://dx.doi.org/10.5935/0103-507X.20180058
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