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Upregulation of microRNA-17-5p contributes to hypoxia-induced proliferation in human pulmonary artery smooth muscle cells through modulation of p21 and PTEN

BACKGROUND: Pulmonary arterial smooth muscle cell (PASMC) proliferation in response to hypoxia plays an important role in the vascular remodelling that occurs in hypoxic pulmonary hypertension. MicroRNAs (miRs) are emerging as important regulators in the progression of pulmonary hypertension. In thi...

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Detalles Bibliográficos
Autores principales:	Liu, Guangjie, Hao, Peng, Xu, Jie, Wang, Liming, Wang, Yuchuan, Han, Ruifang, Ying, Ming, Sui, Shuangshuang, Liu, Jinghua, Li, Xuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6180506/ https://www.ncbi.nlm.nih.gov/pubmed/30305109 http://dx.doi.org/10.1186/s12931-018-0902-0

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