Transcriptional defects and reprogramming barriers in somatic cell nuclear reprogramming as revealed by single-embryo RNA sequencing

BACKGROUND: Nuclear reprogramming reinstates totipotency or pluripotency in somatic cells by changing their gene transcription profile. This technology is widely used in medicine, animal husbandry and other industries. However, certain deficiencies severely restrict the applications of this technolo...

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Detalles Bibliográficos
Autores principales: Liu, Yong, Wu, Fengrui, Zhang, Ling, Wu, Xiaoqing, Li, Dengkun, Xin, Jing, Xie, Juan, Kong, Feng, Wang, Wenying, Wu, Qiaoqin, Zhang, Di, Wang, Rong, Gao, Shaorong, Li, Wenyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6180508/
https://www.ncbi.nlm.nih.gov/pubmed/30305014
http://dx.doi.org/10.1186/s12864-018-5091-1

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