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Gain of function in Mycobacterium bovis BCG Moreau due to loss of a transcriptional repressor

The Bacille Calmette-Guérin (BCG) vaccine comprises a family of genetically different strains derived by the loss of genomic regions (RDs) and other mutations. In BCG Moreau, loss of RD16 inactivates rv3405c (*) , encoding a transcriptional repressor that negatively regulates the expression of Rv340...

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Detalles Bibliográficos
Autores principales:	Monteiro-Maia, Renata, Correa, Paloma Rezende, Sousa-Vasconcelos, Periela da Silva, de Pinho, Rosa Teixeira, Mendonça-Lima, Leila
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Instituto Oswaldo Cruz, Ministério da Saúde 2018
Materias:	Short Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6180650/ https://www.ncbi.nlm.nih.gov/pubmed/30328891 http://dx.doi.org/10.1590/0074-02760180267

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