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Obesity and healthcare resource utilization: results from Clinical Practice Research Database (CPRD)

BACKGROUND/OBJECTIVES: The economic burden of obesity and type 2 diabetes (T2D) rises with increasing prevalence. This study estimates the association between obesity, healthcare resource utilization (HCRU) and associated costs in individuals with/without T2D. SUBJECTS/METHODS: This observational co...

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Autores principales: le Roux, C. W., Chubb, B., Nørtoft, E., Borglykke, A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6180713/
https://www.ncbi.nlm.nih.gov/pubmed/30338111
http://dx.doi.org/10.1002/osp4.291
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author le Roux, C. W.
Chubb, B.
Nørtoft, E.
Borglykke, A.
author_facet le Roux, C. W.
Chubb, B.
Nørtoft, E.
Borglykke, A.
author_sort le Roux, C. W.
collection PubMed
description BACKGROUND/OBJECTIVES: The economic burden of obesity and type 2 diabetes (T2D) rises with increasing prevalence. This study estimates the association between obesity, healthcare resource utilization (HCRU) and associated costs in individuals with/without T2D. SUBJECTS/METHODS: This observational cohort study used the United Kingdom Clinical Practice Research Datalink data. Between 1 January 2011 and 31 December 2015, total HCRU costs and individual component costs (hospitalizations, general practitioner contacts, prescriptions) were calculated for individuals linked to the Hospital Episodes Statistics database with/without T2D with normal weight, overweight, class I, II, III obesity. RESULTS: A total of 396,091 individuals were included. Increasing body mass index (BMI) was associated with increased HCRU costs. At each BMI category, costs were greater for individuals with than without T2D. Relative to normal BMI, increasing BMI was positively associated with increased HCRU costs, with similar magnitude regardless of T2D. The total HCRU cost for an individual with class III obesity was 1.4‐fold (£3,695) greater than for normal weight. CONCLUSION: In the United Kingdom, HCRU costs were positively associated with increasing BMI, irrespective of T2D status. The combination of T2D and obesity was associated with higher HCRU costs compared with individuals of the same BMI, without T2D. These findings suggest that prioritizing weight management programmes focused specifically on individuals with obesity and T2D may be more cost‐effective than for those with obesity alone.
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spelling pubmed-61807132018-10-18 Obesity and healthcare resource utilization: results from Clinical Practice Research Database (CPRD) le Roux, C. W. Chubb, B. Nørtoft, E. Borglykke, A. Obes Sci Pract Original Articles BACKGROUND/OBJECTIVES: The economic burden of obesity and type 2 diabetes (T2D) rises with increasing prevalence. This study estimates the association between obesity, healthcare resource utilization (HCRU) and associated costs in individuals with/without T2D. SUBJECTS/METHODS: This observational cohort study used the United Kingdom Clinical Practice Research Datalink data. Between 1 January 2011 and 31 December 2015, total HCRU costs and individual component costs (hospitalizations, general practitioner contacts, prescriptions) were calculated for individuals linked to the Hospital Episodes Statistics database with/without T2D with normal weight, overweight, class I, II, III obesity. RESULTS: A total of 396,091 individuals were included. Increasing body mass index (BMI) was associated with increased HCRU costs. At each BMI category, costs were greater for individuals with than without T2D. Relative to normal BMI, increasing BMI was positively associated with increased HCRU costs, with similar magnitude regardless of T2D. The total HCRU cost for an individual with class III obesity was 1.4‐fold (£3,695) greater than for normal weight. CONCLUSION: In the United Kingdom, HCRU costs were positively associated with increasing BMI, irrespective of T2D status. The combination of T2D and obesity was associated with higher HCRU costs compared with individuals of the same BMI, without T2D. These findings suggest that prioritizing weight management programmes focused specifically on individuals with obesity and T2D may be more cost‐effective than for those with obesity alone. John Wiley and Sons Inc. 2018-08-21 /pmc/articles/PMC6180713/ /pubmed/30338111 http://dx.doi.org/10.1002/osp4.291 Text en © 2018 The Authors. Obesity Science & Practice published by John Wiley & Sons Ltd, World Obesity and The Obesity Society. This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Original Articles
le Roux, C. W.
Chubb, B.
Nørtoft, E.
Borglykke, A.
Obesity and healthcare resource utilization: results from Clinical Practice Research Database (CPRD)
title Obesity and healthcare resource utilization: results from Clinical Practice Research Database (CPRD)
title_full Obesity and healthcare resource utilization: results from Clinical Practice Research Database (CPRD)
title_fullStr Obesity and healthcare resource utilization: results from Clinical Practice Research Database (CPRD)
title_full_unstemmed Obesity and healthcare resource utilization: results from Clinical Practice Research Database (CPRD)
title_short Obesity and healthcare resource utilization: results from Clinical Practice Research Database (CPRD)
title_sort obesity and healthcare resource utilization: results from clinical practice research database (cprd)
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6180713/
https://www.ncbi.nlm.nih.gov/pubmed/30338111
http://dx.doi.org/10.1002/osp4.291
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