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Differentiation of Sendai Virus-Reprogrammed iPSC into β Cells, Compared with Human Pancreatic Islets and Immortalized β Cell Line
BACKGROUND: New sources of insulin-secreting cells are strongly in demand for treatment of diabetes. Induced pluripotent stem cells (iPSCs) have the potential to generate insulin-producing cells (iβ). However, the gene expression profile and secretory function of iβ still need to be validated in com...
Autores principales: | Pellegrini, Silvia, Manenti, Fabio, Chimienti, Raniero, Nano, Rita, Ottoboni, Linda, Ruffini, Francesca, Martino, Gianvito, Ravassard, Philippe, Piemonti, Lorenzo, Sordi, Valeria |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6180725/ https://www.ncbi.nlm.nih.gov/pubmed/30251567 http://dx.doi.org/10.1177/0963689718798564 |
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