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Impact of Aging in Microglia-Mediated D-Serine Balance in the CNS

A mild chronic inflammatory state, like that observed in aged individuals, affects microglial function, inducing a dysfunctional phenotype that potentiates neuroinflammation and cytotoxicity instead of neuroprotection in response to additional challenges. Given that inflammatory activation of microg...

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Detalles Bibliográficos
Autores principales: Beltrán-Castillo, Sebastián, Eugenín, Jaime, von Bernhardi, Rommy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6180939/
https://www.ncbi.nlm.nih.gov/pubmed/30363571
http://dx.doi.org/10.1155/2018/7219732

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