Cargando…

Self-Nanoemulsifying Drug Delivery System of Tetrandrine for Improved Bioavailability: Physicochemical Characterization and Pharmacokinetic Study

The main purpose of this study was to investigate the potential of self-nanoemulsified drug delivery system (SNEDDS) to improve the oral bioavailability of tetrandrine (Tet). SNEDDS was developed by using rational blends of excipients with good solubilizing ability for Tet which was selected based o...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Chunxia, Lv, Li, Guo, Wei, Mo, Lan, Huang, Yaoxing, Li, Guocheng, Huang, Xingzhen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6180989/ https://www.ncbi.nlm.nih.gov/pubmed/30363745 http://dx.doi.org/10.1155/2018/6763057

Ejemplares similares

Self-Nanoemulsifying Drug Delivery System of Lutein: Physicochemical Properties and Effect on Bioavailability of Warfarin
por: Yoo, Juno, et al.
Publicado: (2013)

Self-nanoemulsifying drug delivery system (SNEDDS) mediated improved oral bioavailability of thymoquinone: optimization, characterization, pharmacokinetic, and hepatotoxicity studies
por: Rathore, Charul, et al.
Publicado: (2022)

Self-Nanoemulsifying Drug Delivery Systems for Enhancing Solubility, Permeability, and Bioavailability of Sesamin
por: Wang, Chih-Yuan, et al.
Publicado: (2020)

Novel Solid Self-Nanoemulsifying Drug Delivery System (S-SNEDDS) for Oral Delivery of Olmesartan Medoxomil: Design, Formulation, Pharmacokinetic and Bioavailability Evaluation
por: Nasr, Ali, et al.
Publicado: (2016)

Self-Nanoemulsifying Drug Delivery System for Enhanced Bioavailability of Madecassic Acid: In vitro and in vivo Evaluation
por: Lin, Li, et al.
Publicado: (2023)

Design and optimization of self-nanoemulsifying drug delivery systems for improved bioavailability of cyclovirobuxine D
por: Ke, Zhongcheng, et al.
Publicado: (2016)

Development, Characterization, and in-vivo Pharmacokinetic Study of Lamotrigine Solid Self-Nanoemulsifying Drug Delivery System
por: Abdelmonem, Rehab, et al.
Publicado: (2020)

Enhancement of the Solubility and Bioavailability of Pitavastatin through a Self-Nanoemulsifying Drug Delivery System (SNEDDS)
por: Ashfaq, Mehran, et al.
Publicado: (2022)

Preparation, characterization, and evaluation of antioxidant activity and bioavailability of a self-nanoemulsifying drug delivery system (SNEDDS) for buckwheat flavonoids
por: Zhao, Zhijuan, et al.
Publicado: (2020)

Pharmacokinetics of Quercetin-Loaded Methoxy Poly(ethylene glycol)-b-poly(L-lactic acid) Micelle after Oral Administration in Rats
por: Lv, Li, et al.
Publicado: (2017)

Development of an Orally Bioavailable Isoliquiritigenin Self-Nanoemulsifying Drug Delivery System to Effectively Treat Ovalbumin-Induced Asthma
por: Cao, Mingzhuo, et al.
Publicado: (2020)

Self-Nanoemulsifying Drug Delivery System for Resveratrol: Enhanced Oral Bioavailability and Reduced Physical Fatigue in Rats
por: Yen, Ching-Chi, et al.
Publicado: (2017)

Self-Nanoemulsifying Drug Delivery System (SNEDDS) for Improved Oral Bioavailability of Chlorpromazine: In Vitro and In Vivo Evaluation
por: Baloch, Jeand, et al.
Publicado: (2019)

Erratum to: Preparation, characterization, and evaluation of antioxidant activity and bioavailability of a self-nanoemulsifying drug delivery system (SNEDDS) for buckwheat flavonoids
por: Zhao, Zhijuan, et al.
Publicado: (2021)

Self-Nanoemulsifying Drug Delivery System (SNEDDS) of Apremilast: In Vitro Evaluation and Pharmacokinetics Studies
por: Abushal, Ahad S., et al.
Publicado: (2022)

Custom fractional factorial designs to develop atorvastatin self-nanoemulsifying and nanosuspension delivery systems – enhancement of oral bioavailability
por: Hashem, Fahima M, et al.
Publicado: (2015)

Comparative study on solid self-nanoemulsifying drug delivery and solid dispersion system for enhanced solubility and bioavailability of ezetimibe
por: Rashid, Rehmana, et al.
Publicado: (2015)

Bioavailability of nanoemulsified conjugated linoleic acid for an antiobesity effect
por: Kim, Dongyeop, et al.
Publicado: (2013)

Formulation and Pharmacokinetic Evaluation of Phosal Based Zaltoprofen Solid Self-Nanoemulsifying Drug Delivery System
por: Kalamkar, Rajan, et al.
Publicado: (2019)

Development of self-nanoemulsifying drug delivery systems for the enhancement of solubility and oral bioavailability of fenofibrate, a poorly water-soluble drug
por: Mohsin, Kazi, et al.
Publicado: (2016)

Enhanced Bioavailability of AC1497, a Novel Anticancer Drug Candidate, via a Self-Nanoemulsifying Drug Delivery System
por: Baral, Kshitis Chandra, et al.
Publicado: (2021)

Tadalafil-Loaded Self-Nanoemulsifying Chewable Tablets for Improved Bioavailability: Design, In Vitro, and In Vivo Testing
por: Ali, Hany S. M., et al.
Publicado: (2022)

Development, Characterization, and Pharmacodynamic Evaluation of Hydrochlorothiazide Loaded Self-Nanoemulsifying Drug Delivery Systems
por: Yadav, Pankajkumar S., et al.
Publicado: (2014)

Formulation of Self-Nanoemulsifying Drug Delivery System of Cephalexin: Physiochemical Characterization and Antibacterial Evaluation
por: Zafar, Ameeduzzafar, et al.
Publicado: (2022)

Design and Evaluation of Self-Nanoemulsifying Drug Delivery System of Flutamide
por: Jeevana, Jyothi B, et al.
Publicado: (2011)

Enhancing Oral Bioavailability of Apigenin Using a Bioactive Self-Nanoemulsifying Drug Delivery System (Bio-SNEDDS): In Vitro, In Vivo and Stability Evaluations
por: Kazi, Mohsin, et al.
Publicado: (2020)

Reduced the Food Effect and Enhanced the Oral Bioavailability of Ivacaftor by Self-Nanoemulsifying Drug Delivery System (SNEDDS) Using a New Oil Phase
por: Miao, Yanfei, et al.
Publicado: (2022)

Formulation and development of a self-nanoemulsifying drug delivery system of irbesartan
por: Patel, Jaydeep, et al.
Publicado: (2011)

Enhanced Topical Delivery of Tetrandrine by Ethosomes for Treatment of Arthritis
por: Fan, Chao, et al.
Publicado: (2013)

Comparison of Three Different Aqueous Microenvironments for Enhancing Oral Bioavailability of Sildenafil: Solid Self-Nanoemulsifying Drug Delivery System, Amorphous Microspheres and Crystalline Microspheres
por: Kim, Jung Suk, et al.
Publicado: (2021)

New lumefantrine self nanoemulsifying delivery system – will it by-pass lymphatic transport mechanisms?
por: Srinivas, Nuggehally R
Publicado: (2013)

Self-nanoemulsifying drug-delivery systems for potentiated anti-inflammatory activity of diacerein
por: Eltobshi, Amal Ahmed, et al.
Publicado: (2018)

Hepatoprotective Effects of Bioflavonoid Luteolin Using Self-Nanoemulsifying Drug Delivery System
por: Shakeel, Faiyaz, et al.
Publicado: (2021)

Systematic Development of Self-Nanoemulsifying Liquisolid Tablets to Improve the Dissolution and Oral Bioavailability of an Oily Drug, Vitamin K1
por: Tong, Yongtao, et al.
Publicado: (2018)

Design and development of a self-nanoemulsifying drug delivery system for telmisartan for oral drug delivery
por: Patel, Jaydeep, et al.
Publicado: (2011)

The Development and Optimization of Lipid-Based Self-Nanoemulsifying Drug Delivery Systems for the Intravenous Delivery of Propofol
por: Kazi, Mohsin, et al.
Publicado: (2023)

Liquid Crystalline Nanoparticles as an Ophthalmic Delivery System for Tetrandrine: Development, Characterization, and In Vitro and In Vivo Evaluation
por: Liu, Rui, et al.
Publicado: (2016)

Rapid oral transmucosal delivery of zaleplon–lavender oil utilizing self-nanoemulsifying lyophilized tablets technology: development, optimization and pharmacokinetic evaluation
por: Ali, Sarah A., et al.
Publicado: (2022)

Self-Nanoemulsifying Drug Delivery System-Containing the Poorly Absorbed Drug – Valsartan in Post-Bariatric Surgery
por: Huang, Tzu-Hao, et al.
Publicado: (2023)

Preparation and Evaluation of a Self-Nanoemulsifying Drug Delivery System Loaded with Heparin Phospholipid Complex
por: Qiu, Xiao-Lei, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_mgj7fvrk35qucvhnp60904bvaq