Cargando…

Complicated bilateral fungal emphysematous pyelonephritis in a 55-year-old diabetic female: A case report and review of literature

BACKGROUND AND PURPOSE: Emphysematous pyelonephritis (EPN) is a rare and serious disease causing acute renal failure. Diabetes is a major risk factor for this infection. CASE REPORT: Herein, we present the case of a 55-year-old female patient with diabetes and EPN caused by Candida albicans. The inf...

Descripción completa

Detalles Bibliográficos
Autores principales: Lotfali, Ensieh, Abolghasemi, Sara, Gatmirimotahhari, Fatemeh Sadat, Alizadeh, Mohammad, Arab-Mazar, Zahra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Iranian Society of Medical Mycology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6181061/
https://www.ncbi.nlm.nih.gov/pubmed/30324155
http://dx.doi.org/10.18502/cmm.4.2.61
_version_ 1783362332255059968
author Lotfali, Ensieh
Abolghasemi, Sara
Gatmirimotahhari, Fatemeh Sadat
Alizadeh, Mohammad
Arab-Mazar, Zahra
author_facet Lotfali, Ensieh
Abolghasemi, Sara
Gatmirimotahhari, Fatemeh Sadat
Alizadeh, Mohammad
Arab-Mazar, Zahra
author_sort Lotfali, Ensieh
collection PubMed
description BACKGROUND AND PURPOSE: Emphysematous pyelonephritis (EPN) is a rare and serious disease causing acute renal failure. Diabetes is a major risk factor for this infection. CASE REPORT: Herein, we present the case of a 55-year-old female patient with diabetes and EPN caused by Candida albicans. The infection was complicated with endophthalmitis and endocarditis. The results of antifungal susceptibility analysis showed that C. albicans was resistant to fluconazole and susceptible to amphotericin-B and itraconazole. Infection could be controlled by amphotericin-B followed by itraconazole therapy, and the patient was discharged in good condition while receiving antifungal therapy. CONCLUSION: Complicated pyelonephritis with unusual microorganisms should be considered in patients with diabetes and urinary symptoms.
format Online
Article
Text
id pubmed-6181061
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher Iranian Society of Medical Mycology
record_format MEDLINE/PubMed
spelling pubmed-61810612018-10-15 Complicated bilateral fungal emphysematous pyelonephritis in a 55-year-old diabetic female: A case report and review of literature Lotfali, Ensieh Abolghasemi, Sara Gatmirimotahhari, Fatemeh Sadat Alizadeh, Mohammad Arab-Mazar, Zahra Curr Med Mycol Case Report BACKGROUND AND PURPOSE: Emphysematous pyelonephritis (EPN) is a rare and serious disease causing acute renal failure. Diabetes is a major risk factor for this infection. CASE REPORT: Herein, we present the case of a 55-year-old female patient with diabetes and EPN caused by Candida albicans. The infection was complicated with endophthalmitis and endocarditis. The results of antifungal susceptibility analysis showed that C. albicans was resistant to fluconazole and susceptible to amphotericin-B and itraconazole. Infection could be controlled by amphotericin-B followed by itraconazole therapy, and the patient was discharged in good condition while receiving antifungal therapy. CONCLUSION: Complicated pyelonephritis with unusual microorganisms should be considered in patients with diabetes and urinary symptoms. Iranian Society of Medical Mycology 2018-06 /pmc/articles/PMC6181061/ /pubmed/30324155 http://dx.doi.org/10.18502/cmm.4.2.61 Text en © 2018, Published by Mazandaran University of Medical Sciences on behalf of Iranian Society of Medical Mycology and Invasive Fungi Research Center. This is an Open Access article distributed under the terms of the Creative Commons Attribution License, (http://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Lotfali, Ensieh
Abolghasemi, Sara
Gatmirimotahhari, Fatemeh Sadat
Alizadeh, Mohammad
Arab-Mazar, Zahra
Complicated bilateral fungal emphysematous pyelonephritis in a 55-year-old diabetic female: A case report and review of literature
title Complicated bilateral fungal emphysematous pyelonephritis in a 55-year-old diabetic female: A case report and review of literature
title_full Complicated bilateral fungal emphysematous pyelonephritis in a 55-year-old diabetic female: A case report and review of literature
title_fullStr Complicated bilateral fungal emphysematous pyelonephritis in a 55-year-old diabetic female: A case report and review of literature
title_full_unstemmed Complicated bilateral fungal emphysematous pyelonephritis in a 55-year-old diabetic female: A case report and review of literature
title_short Complicated bilateral fungal emphysematous pyelonephritis in a 55-year-old diabetic female: A case report and review of literature
title_sort complicated bilateral fungal emphysematous pyelonephritis in a 55-year-old diabetic female: a case report and review of literature
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6181061/
https://www.ncbi.nlm.nih.gov/pubmed/30324155
http://dx.doi.org/10.18502/cmm.4.2.61
work_keys_str_mv AT lotfaliensieh complicatedbilateralfungalemphysematouspyelonephritisina55yearolddiabeticfemaleacasereportandreviewofliterature
AT abolghasemisara complicatedbilateralfungalemphysematouspyelonephritisina55yearolddiabeticfemaleacasereportandreviewofliterature
AT gatmirimotahharifatemehsadat complicatedbilateralfungalemphysematouspyelonephritisina55yearolddiabeticfemaleacasereportandreviewofliterature
AT alizadehmohammad complicatedbilateralfungalemphysematouspyelonephritisina55yearolddiabeticfemaleacasereportandreviewofliterature
AT arabmazarzahra complicatedbilateralfungalemphysematouspyelonephritisina55yearolddiabeticfemaleacasereportandreviewofliterature