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Complicated bilateral fungal emphysematous pyelonephritis in a 55-year-old diabetic female: A case report and review of literature
BACKGROUND AND PURPOSE: Emphysematous pyelonephritis (EPN) is a rare and serious disease causing acute renal failure. Diabetes is a major risk factor for this infection. CASE REPORT: Herein, we present the case of a 55-year-old female patient with diabetes and EPN caused by Candida albicans. The inf...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Iranian Society of Medical Mycology
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6181061/ https://www.ncbi.nlm.nih.gov/pubmed/30324155 http://dx.doi.org/10.18502/cmm.4.2.61 |
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author | Lotfali, Ensieh Abolghasemi, Sara Gatmirimotahhari, Fatemeh Sadat Alizadeh, Mohammad Arab-Mazar, Zahra |
author_facet | Lotfali, Ensieh Abolghasemi, Sara Gatmirimotahhari, Fatemeh Sadat Alizadeh, Mohammad Arab-Mazar, Zahra |
author_sort | Lotfali, Ensieh |
collection | PubMed |
description | BACKGROUND AND PURPOSE: Emphysematous pyelonephritis (EPN) is a rare and serious disease causing acute renal failure. Diabetes is a major risk factor for this infection. CASE REPORT: Herein, we present the case of a 55-year-old female patient with diabetes and EPN caused by Candida albicans. The infection was complicated with endophthalmitis and endocarditis. The results of antifungal susceptibility analysis showed that C. albicans was resistant to fluconazole and susceptible to amphotericin-B and itraconazole. Infection could be controlled by amphotericin-B followed by itraconazole therapy, and the patient was discharged in good condition while receiving antifungal therapy. CONCLUSION: Complicated pyelonephritis with unusual microorganisms should be considered in patients with diabetes and urinary symptoms. |
format | Online Article Text |
id | pubmed-6181061 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Iranian Society of Medical Mycology |
record_format | MEDLINE/PubMed |
spelling | pubmed-61810612018-10-15 Complicated bilateral fungal emphysematous pyelonephritis in a 55-year-old diabetic female: A case report and review of literature Lotfali, Ensieh Abolghasemi, Sara Gatmirimotahhari, Fatemeh Sadat Alizadeh, Mohammad Arab-Mazar, Zahra Curr Med Mycol Case Report BACKGROUND AND PURPOSE: Emphysematous pyelonephritis (EPN) is a rare and serious disease causing acute renal failure. Diabetes is a major risk factor for this infection. CASE REPORT: Herein, we present the case of a 55-year-old female patient with diabetes and EPN caused by Candida albicans. The infection was complicated with endophthalmitis and endocarditis. The results of antifungal susceptibility analysis showed that C. albicans was resistant to fluconazole and susceptible to amphotericin-B and itraconazole. Infection could be controlled by amphotericin-B followed by itraconazole therapy, and the patient was discharged in good condition while receiving antifungal therapy. CONCLUSION: Complicated pyelonephritis with unusual microorganisms should be considered in patients with diabetes and urinary symptoms. Iranian Society of Medical Mycology 2018-06 /pmc/articles/PMC6181061/ /pubmed/30324155 http://dx.doi.org/10.18502/cmm.4.2.61 Text en © 2018, Published by Mazandaran University of Medical Sciences on behalf of Iranian Society of Medical Mycology and Invasive Fungi Research Center. This is an Open Access article distributed under the terms of the Creative Commons Attribution License, (http://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Lotfali, Ensieh Abolghasemi, Sara Gatmirimotahhari, Fatemeh Sadat Alizadeh, Mohammad Arab-Mazar, Zahra Complicated bilateral fungal emphysematous pyelonephritis in a 55-year-old diabetic female: A case report and review of literature |
title | Complicated bilateral fungal emphysematous pyelonephritis in a 55-year-old diabetic female: A case report and review of literature |
title_full | Complicated bilateral fungal emphysematous pyelonephritis in a 55-year-old diabetic female: A case report and review of literature |
title_fullStr | Complicated bilateral fungal emphysematous pyelonephritis in a 55-year-old diabetic female: A case report and review of literature |
title_full_unstemmed | Complicated bilateral fungal emphysematous pyelonephritis in a 55-year-old diabetic female: A case report and review of literature |
title_short | Complicated bilateral fungal emphysematous pyelonephritis in a 55-year-old diabetic female: A case report and review of literature |
title_sort | complicated bilateral fungal emphysematous pyelonephritis in a 55-year-old diabetic female: a case report and review of literature |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6181061/ https://www.ncbi.nlm.nih.gov/pubmed/30324155 http://dx.doi.org/10.18502/cmm.4.2.61 |
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