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Characterization of clinical grade CD19 chimeric antigen receptor T cells produced using automated CliniMACS Prodigy system
BACKGROUND: Chimeric antigen receptor (CAR) T-cell therapy is highly effective for treating acute lymphoblastic leukemia and non-Hodgkin’s lymphoma with high rate complete responses. However, the broad clinical application of CAR T-cell therapy has been challenging, largely due to the lack of widesp...
Autores principales: | Zhang, Wei, Jordan, Kimberly R, Schulte, Brian, Purev, Enkhtsetseg |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6181073/ https://www.ncbi.nlm.nih.gov/pubmed/30323566 http://dx.doi.org/10.2147/DDDT.S175113 |
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