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The evaluation of anaemia in an older primary care population: retrospective population-based study

BACKGROUND: Anaemia is common in older people and the identification of potentially reversible haematinic deficiencies relies on appropriate investigation, often undertaken in primary care. AIM: To determine the laboratory prevalence of anaemia, the types of anaemia observed, and the biochemical and...

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Autores principales: McCartney, David, Shine, Brian, Hay, Deborah, Lasserson, Daniel S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal College of General Practitioners 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6181094/
https://www.ncbi.nlm.nih.gov/pubmed/30564686
http://dx.doi.org/10.3399/bjgpopen17X101157
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author McCartney, David
Shine, Brian
Hay, Deborah
Lasserson, Daniel S
author_facet McCartney, David
Shine, Brian
Hay, Deborah
Lasserson, Daniel S
author_sort McCartney, David
collection PubMed
description BACKGROUND: Anaemia is common in older people and the identification of potentially reversible haematinic deficiencies relies on appropriate investigation, often undertaken in primary care. AIM: To determine the laboratory prevalence of anaemia, the types of anaemia observed, and the biochemical and haematological investigations undertaken to characterise any associated haematinic abnormality in older primary care patients. DESIGN & SETTING: A retrospective primary care based study of patients aged >65 years undergoing a full blood count in Oxfordshire, UK between 1 January 2012 and 31 December 2013. METHOD: Consecutive patients aged >65 years with a full blood count were identified retrospectively from a laboratory database. Patient demographics, number of blood tests and additional laboratory investigations requested were recorded. World Health Organisation (WHO) criteria were used to define anaemia. RESULTS: In total 151 473 full blood counts from 53 890 participants were included: 29.6% of patients were anaemic. The majority had a normocytic anaemia (82.4%) and 46.0% of participants with anaemia had no additional investigations performed. The mean haemoglobin was lower in the anaemic group that underwent further investigation than those who did not (Hb 10.68 g/dl versus 11.24 g/dl, P<0.05): 33.2 % of patients with a microcytic anaemia (mean cell volume <80) did not have any markers of iron status measured. CONCLUSION: A large proportion of older adults in primary care with a recent blood test are anaemic, the majority with a normocytic anaemia, with evidence of inadequate investigation. Those with lower haemoglobin are more likely to be further investigated. Further work is needed to understand the approach to anaemia in older adults in primary care.
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spelling pubmed-61810942018-12-18 The evaluation of anaemia in an older primary care population: retrospective population-based study McCartney, David Shine, Brian Hay, Deborah Lasserson, Daniel S BJGP Open Research BACKGROUND: Anaemia is common in older people and the identification of potentially reversible haematinic deficiencies relies on appropriate investigation, often undertaken in primary care. AIM: To determine the laboratory prevalence of anaemia, the types of anaemia observed, and the biochemical and haematological investigations undertaken to characterise any associated haematinic abnormality in older primary care patients. DESIGN & SETTING: A retrospective primary care based study of patients aged >65 years undergoing a full blood count in Oxfordshire, UK between 1 January 2012 and 31 December 2013. METHOD: Consecutive patients aged >65 years with a full blood count were identified retrospectively from a laboratory database. Patient demographics, number of blood tests and additional laboratory investigations requested were recorded. World Health Organisation (WHO) criteria were used to define anaemia. RESULTS: In total 151 473 full blood counts from 53 890 participants were included: 29.6% of patients were anaemic. The majority had a normocytic anaemia (82.4%) and 46.0% of participants with anaemia had no additional investigations performed. The mean haemoglobin was lower in the anaemic group that underwent further investigation than those who did not (Hb 10.68 g/dl versus 11.24 g/dl, P<0.05): 33.2 % of patients with a microcytic anaemia (mean cell volume <80) did not have any markers of iron status measured. CONCLUSION: A large proportion of older adults in primary care with a recent blood test are anaemic, the majority with a normocytic anaemia, with evidence of inadequate investigation. Those with lower haemoglobin are more likely to be further investigated. Further work is needed to understand the approach to anaemia in older adults in primary care. Royal College of General Practitioners 2017-10-04 /pmc/articles/PMC6181094/ /pubmed/30564686 http://dx.doi.org/10.3399/bjgpopen17X101157 Text en Copyright © The Authors https://creativecommons.org/licenses/by/4.0/ This article is Open Access: CC BY license (https://creativecommons.org/licenses/by/4.0/)
spellingShingle Research
McCartney, David
Shine, Brian
Hay, Deborah
Lasserson, Daniel S
The evaluation of anaemia in an older primary care population: retrospective population-based study
title The evaluation of anaemia in an older primary care population: retrospective population-based study
title_full The evaluation of anaemia in an older primary care population: retrospective population-based study
title_fullStr The evaluation of anaemia in an older primary care population: retrospective population-based study
title_full_unstemmed The evaluation of anaemia in an older primary care population: retrospective population-based study
title_short The evaluation of anaemia in an older primary care population: retrospective population-based study
title_sort evaluation of anaemia in an older primary care population: retrospective population-based study
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6181094/
https://www.ncbi.nlm.nih.gov/pubmed/30564686
http://dx.doi.org/10.3399/bjgpopen17X101157
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