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Evaluation of methotrexate-conjugated gadolinium(III) for cancer diagnosis and treatment
BACKGROUND: Gliomas are one of the most common types of primary brain tumors. It is usually evaluated by gadolinium(III)-based contrast agents by magnetic resonance imaging (MRI) in the clinic. Methotrexate (MTX), as a type of folate analog that inhibits the enzyme dihydrofolate reductase, is widely...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Dove Medical Press
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6181113/ https://www.ncbi.nlm.nih.gov/pubmed/30323562 http://dx.doi.org/10.2147/DDDT.S178569 |