Cargando…

Hypokalemic Paralysis Secondary to Renal Tubular Acidosis Revealing Underlying Sjogren's Syndrome

There is a well-established association of Sjogren's syndrome with renal tubular acidosis (RTA). Rarely there is a retrospective diagnosis where the patient presents with RTA and the workup reveals Sjogren's syndrome. Our case report is about a patient who presented with generalized weakne...

Descripción completa

Detalles Bibliográficos
Autores principales: Shahbaz, Amir, Shahid, Muhammad Faizan, Saleem, Hafiz M. Kashif, Malik, Zohra R, Sachmechi, Issac
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6181251/
https://www.ncbi.nlm.nih.gov/pubmed/30345187
http://dx.doi.org/10.7759/cureus.3128
_version_ 1783362358002843648
author Shahbaz, Amir
Shahid, Muhammad Faizan
Saleem, Hafiz M. Kashif
Malik, Zohra R
Sachmechi, Issac
author_facet Shahbaz, Amir
Shahid, Muhammad Faizan
Saleem, Hafiz M. Kashif
Malik, Zohra R
Sachmechi, Issac
author_sort Shahbaz, Amir
collection PubMed
description There is a well-established association of Sjogren's syndrome with renal tubular acidosis (RTA). Rarely there is a retrospective diagnosis where the patient presents with RTA and the workup reveals Sjogren's syndrome. Our case report is about a patient who presented with generalized weakness and hypokalemia, which upon further workup turned out to be RTA. Various tests were performed to find out the cause of RTA. A favorable profile for the anti-nuclear antibody, anti-Ro/SSA, and anti-La/SSB was consistent with Sjogren's syndrome. Treatment with corticosteroid improved hypokalemia. The patient did not have typical glandular symptoms of Sjogren's syndrome, and follow-up is needed to see whether the patient develops symptoms in the future and to prevent any possible complication.
format Online
Article
Text
id pubmed-6181251
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher Cureus
record_format MEDLINE/PubMed
spelling pubmed-61812512018-10-19 Hypokalemic Paralysis Secondary to Renal Tubular Acidosis Revealing Underlying Sjogren's Syndrome Shahbaz, Amir Shahid, Muhammad Faizan Saleem, Hafiz M. Kashif Malik, Zohra R Sachmechi, Issac Cureus Internal Medicine There is a well-established association of Sjogren's syndrome with renal tubular acidosis (RTA). Rarely there is a retrospective diagnosis where the patient presents with RTA and the workup reveals Sjogren's syndrome. Our case report is about a patient who presented with generalized weakness and hypokalemia, which upon further workup turned out to be RTA. Various tests were performed to find out the cause of RTA. A favorable profile for the anti-nuclear antibody, anti-Ro/SSA, and anti-La/SSB was consistent with Sjogren's syndrome. Treatment with corticosteroid improved hypokalemia. The patient did not have typical glandular symptoms of Sjogren's syndrome, and follow-up is needed to see whether the patient develops symptoms in the future and to prevent any possible complication. Cureus 2018-08-10 /pmc/articles/PMC6181251/ /pubmed/30345187 http://dx.doi.org/10.7759/cureus.3128 Text en Copyright © 2018, Shahbaz et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Shahbaz, Amir
Shahid, Muhammad Faizan
Saleem, Hafiz M. Kashif
Malik, Zohra R
Sachmechi, Issac
Hypokalemic Paralysis Secondary to Renal Tubular Acidosis Revealing Underlying Sjogren's Syndrome
title Hypokalemic Paralysis Secondary to Renal Tubular Acidosis Revealing Underlying Sjogren's Syndrome
title_full Hypokalemic Paralysis Secondary to Renal Tubular Acidosis Revealing Underlying Sjogren's Syndrome
title_fullStr Hypokalemic Paralysis Secondary to Renal Tubular Acidosis Revealing Underlying Sjogren's Syndrome
title_full_unstemmed Hypokalemic Paralysis Secondary to Renal Tubular Acidosis Revealing Underlying Sjogren's Syndrome
title_short Hypokalemic Paralysis Secondary to Renal Tubular Acidosis Revealing Underlying Sjogren's Syndrome
title_sort hypokalemic paralysis secondary to renal tubular acidosis revealing underlying sjogren's syndrome
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6181251/
https://www.ncbi.nlm.nih.gov/pubmed/30345187
http://dx.doi.org/10.7759/cureus.3128
work_keys_str_mv AT shahbazamir hypokalemicparalysissecondarytorenaltubularacidosisrevealingunderlyingsjogrenssyndrome
AT shahidmuhammadfaizan hypokalemicparalysissecondarytorenaltubularacidosisrevealingunderlyingsjogrenssyndrome
AT saleemhafizmkashif hypokalemicparalysissecondarytorenaltubularacidosisrevealingunderlyingsjogrenssyndrome
AT malikzohrar hypokalemicparalysissecondarytorenaltubularacidosisrevealingunderlyingsjogrenssyndrome
AT sachmechiissac hypokalemicparalysissecondarytorenaltubularacidosisrevealingunderlyingsjogrenssyndrome