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Therapeutic potential of tranilast for the treatment of chronic graft-versus-host disease in mice

Chronic graft-versus-host disease (cGVHD) is a marked complication of hematopoietic stem cell transplantation, and multiple organs can be affected by cGVHD-induced inflammation and fibrosis. In clinical settings, immunosuppressive agents have been the last resort to treat cGVHD. However, it has been...

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Detalles Bibliográficos
Autores principales: Mukai, Shin, Ogawa, Yoko, Saya, Hideyuki, Kawakami, Yutaka, Tsubota, Kazuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6181285/
https://www.ncbi.nlm.nih.gov/pubmed/30307955
http://dx.doi.org/10.1371/journal.pone.0203742