Cargando…

The BH3 only Bcl-2 family member BNIP3 regulates cellular proliferation

The BH3-only family member BNIP3 has been described as either promoting cell survival or cell death. This depends upon the level of BNIP3 expression and its cellular localization. Increased BNIP3 expression under hypoxia contributes to cell death through increased mitochondrial dysfunction. Furtherm...

Descripción completa

Detalles Bibliográficos
Autores principales:	Singh, Amandeep, Azad, Meghan, Shymko, Miriam D., Henson, Elizabeth S., Katyal, Sachin, Eisenstat, David D., Gibson, Spencer B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6181300/ https://www.ncbi.nlm.nih.gov/pubmed/30307949 http://dx.doi.org/10.1371/journal.pone.0204792

Ejemplares similares

BCL2DB: database of BCL-2 family members and BH3-only proteins
por: Rech de Laval, Valentine, et al.
Publicado: (2014)

BNIP3 acts as transcriptional repressor of death receptor-5 expression and prevents TRAIL-induced cell death in gliomas
por: Burton, T R, et al.
Publicado: (2013)

Bax activation by the BH3-only protein Puma promotes cell dependence on antiapoptotic Bcl-2 family members
por: Gallenne, Tristan, et al.
Publicado: (2009)

The Bcl-2 Homology-3 Domain (BH3)-Only Proteins, Bid, DP5/Hrk, and BNip3L, Are Upregulated in Reactive Astrocytes of End-Stage Mutant SOD1 Mouse Spinal Cord
por: Duval, Nathan, et al.
Publicado: (2018)

Structural Investigation of Orf Virus Bcl-2 Homolog ORFV125 Interactions with BH3-Motifs from BH3-Only Proteins Puma and Hrk
por: Suraweera, Chathura D., et al.
Publicado: (2021)

BH3-profiling identifies heterogeneous dependency on Bcl-2 family members in Multiple Myeloma and predicts sensitivity to BH3 mimetics
por: Touzeau, Cyrille, et al.
Publicado: (2015)

The restricted binding repertoire of Bcl-B leaves Bim as the universal BH3-only prosurvival Bcl-2 protein antagonist
por: Rautureau, G J P, et al.
Publicado: (2012)

Prognostic impact of the expression/phosphorylation of the BH3-only proteins of the BCL-2 family in glioblastoma multiforme
por: Cartron, P F, et al.
Publicado: (2012)

The role of BH3-only protein Bim extends beyond inhibiting Bcl-2–like prosurvival proteins
por: Mérino, Delphine, et al.
Publicado: (2009)

Molecular Interactions of Prodiginines with the BH3 Domain of Anti-Apoptotic Bcl-2 Family Members
por: Hosseini, Ali, et al.
Publicado: (2013)

Mutual Regulation of Bcl-2 Proteins Independent of the BH3 Domain as Shown by the BH3-Lacking Protein Bcl-x(AK)
por: Plötz, Michael, et al.
Publicado: (2012)

MOMP in the absence of BH3-only proteins
por: García Sáez, Ana J., et al.
Publicado: (2016)

Combined inhibition of aurora kinases and Bcl-xL induces apoptosis through select BH3-only proteins
por: Li, Jian, et al.
Publicado: (2023)

Loss of the Pro-Apoptotic BH3-only Bcl-2 Family Member Bim Inhibits BCR Stimulation–induced Apoptosis and Deletion of Autoreactive B Cells
por: Enders, Anselm, et al.
Publicado: (2003)

Proapoptotic BH3-only proteins trigger membrane integration of prosurvival Bcl-w and neutralize its activity
por: Wilson-Annan, Julie, et al.
Publicado: (2003)

BH3-only proteins, Bmf and Bim, in autophagy
por: Delgado, Monica, et al.
Publicado: (2013)

BH3-only proteins are dispensable for apoptosis induced by pharmacological inhibition of both MCL-1 and BCL-X(L)
por: Greaves, Georgia, et al.
Publicado: (2018)

Telomerase Reverse Transcriptase Contains a BH3-Like Motif and Interacts with BCL-2 Family Members
por: Jin, Young, et al.
Publicado: (2018)

The BH3-only proteins BIM and PUMA are not critical for the reticulocyte apoptosis caused by loss of the pro-survival protein BCL-XL
por: Delbridge, Alex RD, et al.
Publicado: (2017)

Estrogen Regulation of Anti-Apoptotic Bcl-2 Family Member Mcl-1 Expression in Breast Cancer Cells
por: Schacter, Jennifer L., et al.
Publicado: (2014)

BAFF regulates B cell survival by downregulating the BH3-only family member Bim via the ERK pathway
por: Craxton, Andrew, et al.
Publicado: (2005)

Apolipoprotein L2 contains a BH3-like domain but it does not behave as a BH3-only protein
por: Galindo-Moreno, J, et al.
Publicado: (2014)

The pro-apoptotic paradox: the BH3-only protein Bcl-2 interacting killer (Bik) is prognostic for unfavorable outcomes in breast cancer
por: Pandya, Vrajesh, et al.
Publicado: (2016)

Functional disparities among BCL-2 members in tonsillar and leukemic B-cell subsets assessed by BH3-mimetic profiling
por: Peperzak, Victor, et al.
Publicado: (2017)

BNIP3 (BCL2 interacting protein 3) regulates pluripotency by modulating mitochondrial homeostasis via mitophagy
por: Liu, Kun, et al.
Publicado: (2022)

BH3-Only Protein BIM Mediates Heat Shock-Induced Apoptosis
por: Mahajan, Indra M., et al.
Publicado: (2014)

Development of a lytic peptide derived from BH3-only proteins
por: Liu, Q, et al.
Publicado: (2016)

Role of BH3-only protein Bim in autoimmune and degenerative diseases
por: Bouillet, P, et al.
Publicado: (2003)

BH3-only proteins: the thorny end of the ER stress response
por: Glab, Jason A, et al.
Publicado: (2017)

Targeting BCL-2–expressing basal-like breast cancer with BH3-mimetics
por: Oakes, SR, et al.
Publicado: (2012)

In non-transformed cells Bak activates upon loss of anti-apoptotic Bcl-X(L) and Mcl-1 but in the absence of active BH3-only proteins
por: Senft, D, et al.
Publicado: (2015)

Human Herpesvirus 8 Interferon Regulatory Factor-Mediated BH3-Only Protein Inhibition via Bid BH3-B Mimicry
por: Choi, Young Bong, et al.
Publicado: (2012)

DNA methylation of the promoter region of bnip3 and bnip3l genes induced by metabolic programming
por: Veron, Vincent, et al.
Publicado: (2018)

BH3-only protein Noxa contributes to apoptotic control of stress-erythropoiesis
por: Wensveen, Felix M., et al.
Publicado: (2013)

The BH3-only protein Bad is dispensable for TNF-mediated cell death
por: Ottina, E, et al.
Publicado: (2015)

BH3-Only Proteins Noxa and Puma Are Key Regulators of Induced Apoptosis
por: Roufayel, Rabih, et al.
Publicado: (2022)

Evidence for existence of an apoptosis‐inducing BH3‐only protein, sayonara, in Drosophila
por: Ikegawa, Yuko, et al.
Publicado: (2023)

BCL-2 family deregulation in colorectal cancer: potential for BH3 mimetics in therapy
por: Ramesh, Prashanthi, et al.
Publicado: (2020)

Glucose Induces Pancreatic Islet Cell Apoptosis That Requires the BH3-Only Proteins Bim and Puma and Multi-BH Domain Protein Bax
por: McKenzie, Mark D., et al.
Publicado: (2010)

Misoprostol treatment prevents hypoxia-induced cardiac dysfunction through a 14-3-3 and PKA regulatory motif on Bnip3
por: Martens, Matthew D., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_oljjrob13gcj82j0mh1tu42h7k