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Transcription factor programming of human ES cells generates functional neurons expressing both upper and deep layer cortical markers

Human neurodegenerative disorders affect specific types of cortical neurons. Efficient protocols for the generation of such neurons for cell replacement, disease modeling and drug screening are highly warranted. Current methods for the production of cortical neurons from human embryonic stem (ES) ce...

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Detalles Bibliográficos
Autores principales:	Miskinyte, Giedre, Grønning Hansen, Marita, Monni, Emanuela, Lam, Matti, Bengzon, Johan, Lindvall, Olle, Ahlenius, Henrik, Kokaia, Zaal
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6181302/ https://www.ncbi.nlm.nih.gov/pubmed/30307948 http://dx.doi.org/10.1371/journal.pone.0204688

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