Distinct virulence ranges for infection of mice by Bordetella pertussis revealed by engineering of the sensor-kinase BvgS

The whooping cough agent Bordetella pertussis coordinately regulates the expression of its virulence factors with the two-component system BvgAS. In laboratory conditions, specific chemical modulators are used to trigger phenotypic modulation of B. pertussis from its default virulent Bvg(+) phase to...

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Detalles Bibliográficos
Autores principales: Lesne, Elodie, Coutte, Loic, Solans, Luis, Slupek, Stephanie, Debrie, Anne-Sophie, Dhennin, Véronique, Froguel, Philippe, Hot, David, Locht, Camille, Antoine, Rudy, Jacob-Dubuisson, Françoise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6181320/
https://www.ncbi.nlm.nih.gov/pubmed/30307950
http://dx.doi.org/10.1371/journal.pone.0204861

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