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Serum asunaprevir concentrations showing correlation with the extent of liver fibrosis as a factor inducing liver injuries in patients with genotype-1b hepatitis C virus receiving daclatasvir plus asunaprevir therapy
AIMS: Liver injury can occur during antiviral therapies with direct-acting antivirals (DAAs), potentially necessitating discontinuation of the therapies, with consequent worsening of the sustained viral response (SVR) rates, in patients with hepatitis C virus (HCV). To clarify the mechanisms involve...
Autores principales: | Uchida, Yoshihito, Naiki, Kayoko, Kouyama, Jun-ichi, Sugawara, Kayoko, Nakao, Masamitsu, Motoya, Daisuke, Inao, Mie, Nakayama, Nobuaki, Imai, Yukinori, Tomiya, Tomoaki, Mochida, Satoshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6181393/ https://www.ncbi.nlm.nih.gov/pubmed/30308053 http://dx.doi.org/10.1371/journal.pone.0205600 |
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