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ALDH1A1 expression is associated with poor differentiation, ‘right-sidedness’ and poor survival in human colorectal cancer

BACKGROUND: Aldehyde dehydrogenase 1A1 (ALDH1A1) encodes an enzyme that oxidizes aldehydes to their corresponding carboxylic acids. In colorectal cancer ALDH1A1 marks cancer stem cells and plays putative roles in tumor progression and drug resistance. However, the potential value of ALDH1A1 as a dia...

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Detalles Bibliográficos
Autores principales: van der Waals, Lizet M., Borel Rinkes, Inne H. M., Kranenburg, Onno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6181398/
https://www.ncbi.nlm.nih.gov/pubmed/30308036
http://dx.doi.org/10.1371/journal.pone.0205536