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Exploring the impact of inoculum dose on host immunity and morbidity to inform model-based vaccine design
Vaccination is an effective method to protect against infectious diseases. An important consideration in any vaccine formulation is the inoculum dose, i.e., amount of antigen or live attenuated pathogen that is used. Higher levels generally lead to better stimulation of the immune response but might...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6181424/ https://www.ncbi.nlm.nih.gov/pubmed/30273336 http://dx.doi.org/10.1371/journal.pcbi.1006505 |