Tau Activates Transposable Elements in Alzheimer’s Disease

Aging and neurodegenerative disease are characterized by genomic instability in neurons, including aberrant activation and mobilization of transposable elements (TEs). Integrating studies of human postmortem brain tissue and Drosophila melanogaster models, we investigate TE activation in association...

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Detalles Bibliográficos
Autores principales: Guo, Caiwei, Jeong, Hyun-Hwan, Hsieh, Yi-Chen, Klein, Hans-Ulrich, Bennett, David A., De Jager, Philip L., Liu, Zhandong, Shulman, Joshua M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6181645/
https://www.ncbi.nlm.nih.gov/pubmed/29874575
http://dx.doi.org/10.1016/j.celrep.2018.05.004

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