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A cysteine-based molecular code informs collagen C-propeptide assembly
Fundamental questions regarding collagen biosynthesis, especially with respect to the molecular origins of homotrimeric versus heterotrimeric assembly, remain unanswered. Here, we demonstrate that the presence or absence of a single cysteine in type-I collagen’s C-propeptide domain is a key factor g...
Autores principales: | DiChiara, Andrew S., Li, Rasia C., Suen, Patreece H., Hosseini, Azade S., Taylor, Rebecca J., Weickhardt, Alexander F., Malhotra, Diya, McCaslin, Darrell R., Shoulders, Matthew D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6181919/ https://www.ncbi.nlm.nih.gov/pubmed/30310058 http://dx.doi.org/10.1038/s41467-018-06185-2 |
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