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The CTLA-4 rs231775 GG genotype is associated with favorable 90-day survival in Caucasian patients with sepsis
Cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) is a surface protein on T cells, that has an inhibitory effect on the host immune reaction and prevents overreaction of the immune system. Because the functional single-nucleotide polymorphism (SNP) rs231775 of the CTLA-4 gene is associated with a...
Autores principales: | Mewes, Caspar, Büttner, Benedikt, Hinz, José, Alpert, Ayelet, Popov, Aron Frederik, Ghadimi, Michael, Beissbarth, Tim, Tzvetkov, Mladen, Shen-Orr, Shai, Bergmann, Ingo, Mansur, Ashham |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6181961/ https://www.ncbi.nlm.nih.gov/pubmed/30310101 http://dx.doi.org/10.1038/s41598-018-33246-9 |
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