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Development of lentiviral vectors for efficient glutamatergic-selective gene expression in cultured hippocampal neurons

Targeting gene expression to a particular subset of neurons helps study the cellular function of the nervous system. Although neuron-specific promoters, such as the synapsin I promoter and the α-CaMKII promoter, are known to exhibit selectivity for excitatory glutamatergic neurons in vivo, the cell...

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Detalles Bibliográficos
Autores principales: Egashira, Yoshihiro, Mori, Yasunori, Yanagawa, Yuchio, Takamori, Shigeo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6181963/
https://www.ncbi.nlm.nih.gov/pubmed/30310105
http://dx.doi.org/10.1038/s41598-018-33509-5