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Predicting CTCF-mediated chromatin interactions by integrating genomic and epigenomic features
The CCCTC-binding zinc-finger protein (CTCF)-mediated network of long-range chromatin interactions is important for genome organization and function. Although this network has been considered largely invariant, we find that it exhibits extensive cell-type-specific interactions that contribute to cel...
Autores principales: | Kai, Yan, Andricovich, Jaclyn, Zeng, Zhouhao, Zhu, Jun, Tzatsos, Alexandros, Peng, Weiqun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6181989/ https://www.ncbi.nlm.nih.gov/pubmed/30310060 http://dx.doi.org/10.1038/s41467-018-06664-6 |
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