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Predicting CTCF-mediated chromatin interactions by integrating genomic and epigenomic features

The CCCTC-binding zinc-finger protein (CTCF)-mediated network of long-range chromatin interactions is important for genome organization and function. Although this network has been considered largely invariant, we find that it exhibits extensive cell-type-specific interactions that contribute to cel...

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Detalles Bibliográficos
Autores principales: Kai, Yan, Andricovich, Jaclyn, Zeng, Zhouhao, Zhu, Jun, Tzatsos, Alexandros, Peng, Weiqun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6181989/
https://www.ncbi.nlm.nih.gov/pubmed/30310060
http://dx.doi.org/10.1038/s41467-018-06664-6

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