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Rifampicin can induce antibiotic tolerance in mycobacteria via paradoxical changes in rpoB transcription

Metrics commonly used to describe antibiotic efficacy rely on measurements performed on bacterial populations. However, certain cells in a bacterial population can continue to grow and divide, even at antibiotic concentrations that kill the majority of cells, in a phenomenon known as antibiotic tole...

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Detalles Bibliográficos
Autores principales: Zhu, Jun-Hao, Wang, Bi-Wei, Pan, Miaomiao, Zeng, Yu-Na, Rego, Hesper, Javid, Babak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6181997/
https://www.ncbi.nlm.nih.gov/pubmed/30310059
http://dx.doi.org/10.1038/s41467-018-06667-3

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