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Rifampicin can induce antibiotic tolerance in mycobacteria via paradoxical changes in rpoB transcription
Metrics commonly used to describe antibiotic efficacy rely on measurements performed on bacterial populations. However, certain cells in a bacterial population can continue to grow and divide, even at antibiotic concentrations that kill the majority of cells, in a phenomenon known as antibiotic tole...
Autores principales: | Zhu, Jun-Hao, Wang, Bi-Wei, Pan, Miaomiao, Zeng, Yu-Na, Rego, Hesper, Javid, Babak |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6181997/ https://www.ncbi.nlm.nih.gov/pubmed/30310059 http://dx.doi.org/10.1038/s41467-018-06667-3 |
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