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Hydroxyurea Treated β-Thalassemia Children Demonstrate a Shift in Metabolism Towards Healthy Pattern
Augmentation of fetal hemoglobin (HbF) production has been an enduring therapeutic objective in β-thalassemia patients for which hydroxyurea (HU) has largely been the drug of choice and the most cost-effective approach. A serum metabolomics study on 40 patients with β-thalassemia prior to and after...
Autores principales: | Iqbal, Ayesha, Ansari, Saqib Hussain, Parveen, Sadia, Khan, Ishtiaq Ahmad, Siddiqui, Amna Jabbar, Musharraf, Syed Ghulam |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6182004/ https://www.ncbi.nlm.nih.gov/pubmed/30310134 http://dx.doi.org/10.1038/s41598-018-33540-6 |
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