Inflammation: A Network in the Pathogenesis of Status Epilepticus

Status epilepticus (SE) is an abnormally prolonged or recurrent epileptic seizure that is a serious, life-threatening medical emergency. Notably, it requires prompt and aggressive treatment. SE is characterized by high mortality and morbidity. However, its pathogenesis remains unclear. Numerous stud...

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Detalles Bibliográficos
Autores principales: Wang, Ming, Chen, Yinghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6182087/
https://www.ncbi.nlm.nih.gov/pubmed/30344475
http://dx.doi.org/10.3389/fnmol.2018.00341
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author Wang, Ming
Chen, Yinghui
author_facet Wang, Ming
Chen, Yinghui
author_sort Wang, Ming
collection PubMed
description Status epilepticus (SE) is an abnormally prolonged or recurrent epileptic seizure that is a serious, life-threatening medical emergency. Notably, it requires prompt and aggressive treatment. SE is characterized by high mortality and morbidity. However, its pathogenesis remains unclear. Numerous studies of SE have reported widespread brain inflammation, suggesting that inflammation plays a vital role in the occurrence and development of SE. This mini review article reviews the current knowledge with regard to the role of inflammation in SE.
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spelling pubmed-61820872018-10-19 Inflammation: A Network in the Pathogenesis of Status Epilepticus Wang, Ming Chen, Yinghui Front Mol Neurosci Neuroscience Status epilepticus (SE) is an abnormally prolonged or recurrent epileptic seizure that is a serious, life-threatening medical emergency. Notably, it requires prompt and aggressive treatment. SE is characterized by high mortality and morbidity. However, its pathogenesis remains unclear. Numerous studies of SE have reported widespread brain inflammation, suggesting that inflammation plays a vital role in the occurrence and development of SE. This mini review article reviews the current knowledge with regard to the role of inflammation in SE. Frontiers Media S.A. 2018-10-05 /pmc/articles/PMC6182087/ /pubmed/30344475 http://dx.doi.org/10.3389/fnmol.2018.00341 Text en Copyright © 2018 Wang and Chen. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Neuroscience
Wang, Ming
Chen, Yinghui
Inflammation: A Network in the Pathogenesis of Status Epilepticus
title Inflammation: A Network in the Pathogenesis of Status Epilepticus
title_full Inflammation: A Network in the Pathogenesis of Status Epilepticus
title_fullStr Inflammation: A Network in the Pathogenesis of Status Epilepticus
title_full_unstemmed Inflammation: A Network in the Pathogenesis of Status Epilepticus
title_short Inflammation: A Network in the Pathogenesis of Status Epilepticus
title_sort inflammation: a network in the pathogenesis of status epilepticus
topic Neuroscience
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6182087/
https://www.ncbi.nlm.nih.gov/pubmed/30344475
http://dx.doi.org/10.3389/fnmol.2018.00341
work_keys_str_mv AT wangming inflammationanetworkinthepathogenesisofstatusepilepticus
AT chenyinghui inflammationanetworkinthepathogenesisofstatusepilepticus

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