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A mating-type mutagenesis screen identifies a zinc-finger protein required for specific DNA excision events in Paramecium
In the ciliate Paramecium tetraurelia, functional genes are reconstituted during development of the somatic macronucleus through the precise excision of ∼45 000 single-copy Internal Eliminated Sequences (IESs), thought to be the degenerate remnants of ancient transposon insertions. Like introns, IES...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6182129/ https://www.ncbi.nlm.nih.gov/pubmed/30165457 http://dx.doi.org/10.1093/nar/gky772 |