Modulation of the HIV nucleocapsid dynamics finely tunes its RNA-binding properties during virion genesis

During HIV-1 assembly and budding, Gag protein, in particular the C-terminal domain containing the nucleocapsid domain (NCd), p1 and p6, is the site of numerous interactions with viral and cellular factors. Most in vitro studies of Gag have used constructs lacking p1 and p6. Here, using NMR spectros...

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Detalles Bibliográficos
Autores principales: Mouhand, Assia, Belfetmi, Anissa, Catala, Marjorie, Larue, Valéry, Zargarian, Loussiné, Brachet, Franck, Gorelick, Robert J, Van Heijenoort, Carine, Mirambeau, Gilles, Barraud, Pierre, Mauffret, Olivier, Tisné, Carine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
RNA and RNA-protein complexes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6182130/
https://www.ncbi.nlm.nih.gov/pubmed/29986076
http://dx.doi.org/10.1093/nar/gky612

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