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Synthetic control systems for high performance gene expression in mammalian cells
Tunable induction of gene expression is an essential tool in biology and biotechnology. In spite of that, current induction systems often exhibit unpredictable behavior and performance shortcomings, including high sensitivity to transactivator dosage and plasmid take-up variation, and excessive cons...
Autores principales: | Lillacci, Gabriele, Benenson, Yaakov, Khammash, Mustafa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6182142/ https://www.ncbi.nlm.nih.gov/pubmed/30203050 http://dx.doi.org/10.1093/nar/gky795 |
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