Aminoglycoside ribosome interactions reveal novel conformational states at ambient temperature

The bacterial 30S ribosomal subunit is a primary antibiotic target. Despite decades of discovery, the mechanisms by which antibiotic binding induces ribosomal dysfunction are not fully understood. Ambient temperature crystallographic techniques allow more biologically relevant investigation of how l...

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Detalles Bibliográficos
Autores principales: O’Sullivan, Mary E, Poitevin, Frédéric, Sierra, Raymond G, Gati, Cornelius, Dao, E Han, Rao, Yashas, Aksit, Fulya, Ciftci, Halilibrahim, Corsepius, Nicholas, Greenhouse, Robert, Hayes, Brandon, Hunter, Mark S, Liang, Mengling, McGurk, Alex, Mbgam, Paul, Obrinsky, Trevor, Pardo-Avila, Fátima, Seaberg, Matthew H, Cheng, Alan G, Ricci, Anthony J, DeMirci, Hasan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6182148/
https://www.ncbi.nlm.nih.gov/pubmed/30113694
http://dx.doi.org/10.1093/nar/gky693

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6182148/
https://www.ncbi.nlm.nih.gov/pubmed/30113694
http://dx.doi.org/10.1093/nar/gky693

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