Molecular organization of the type II-A CRISPR adaptation module and its interaction with Cas9 via Csn2

Clustered regularly interspaced short palindromic repeats (CRISPRs) and CRISPR-associated (Cas) proteins provide microbial adaptive immunity against invading foreign nucleic acids. In type II-A CRISPR–Cas systems, the Cas1–Cas2 integrase complex and the subtype-specific Csn2 comprise the CRISPR adap...

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Detalles Bibliográficos
Autores principales: Ka, Donghyun, Jang, Dong Man, Han, Byung Woo, Bae, Euiyoung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6182153/
https://www.ncbi.nlm.nih.gov/pubmed/30102386
http://dx.doi.org/10.1093/nar/gky702

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