Deacetylation of NAT10 by Sirt1 promotes the transition from rRNA biogenesis to autophagy upon energy stress

Anabolism and catabolism are tightly regulated according to the cellular energy supply. Upon energy stress, ribosomal RNA (rRNA) biogenesis is inhibited, and autophagy is induced. However, the mechanism linking rRNA biogenesis and autophagy is unclear. Here, we demonstrate that the nucleolar protein...

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Detalles Bibliográficos
Autores principales: Liu, Xiaofeng, Cai, Shiying, Zhang, Chunfeng, Liu, Zhenzhen, Luo, Jianyuan, Xing, Baocai, Du, Xiaojuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6182161/
https://www.ncbi.nlm.nih.gov/pubmed/30165671
http://dx.doi.org/10.1093/nar/gky777

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