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A synthetic free fatty acid-regulated transgene switch in mammalian cells and mice

Trigger-inducible transgene expression systems are utilized in biopharmaceutical manufacturing and also to enable controlled release of therapeutic agents in vivo. We considered that free fatty acids (FFAs), which are dietary components, signaling molecules and important biomarkers, would be attract...

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Detalles Bibliográficos
Autores principales:	Liu, Ying, Charpin-El Hamri, Ghislaine, Ye, Haifeng, Fussenegger, Martin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2018
Materias:	Synthetic Biology and Bioengineering
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6182168/ https://www.ncbi.nlm.nih.gov/pubmed/30219861 http://dx.doi.org/10.1093/nar/gky805

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