Widespread airway distribution and short-term phenotypic correction of cystic fibrosis pigs following aerosol delivery of piggyBac/adenovirus

Cystic fibrosis (CF) is a common genetic disease caused by mutations in the gene coding for cystic fibrosis transmembrane conductance regulator (CFTR). Although CF affects multiple organ systems, chronic bacterial infections and inflammation in the lung are the leading causes of morbidity and mortal...

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Detalles Bibliográficos
Autores principales: Cooney, Ashley L, Singh, Brajesh K, Loza, Laura Marquez, Thornell, Ian M, Hippee, Camilla E, Powers, Linda S, Ostedgaard, Lynda S, Meyerholz, David K, Wohlford-Lenane, Chris, Stoltz, David A, B. McCray, Paul, Sinn, Patrick L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6182177/
https://www.ncbi.nlm.nih.gov/pubmed/30165523
http://dx.doi.org/10.1093/nar/gky773

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