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Non Catether Induced Renal and Inferior Vena Cava Trombosis in a Neonate: A Case Report

BACKGROUND: Neonatal renal vein thrombosis is the most common vascular condition in the newborn kidney, which could lead to serious complication in infants. CASE REPORT: We report a case of the unilateral renal vein and inferior vena cava thrombosis, presented with gross hematuria and thrombocytopen...

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Autores principales: Aluloska, Natasha, Janchevska, Snezana, Tasic, Velibor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Republic of Macedonia 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6182507/
https://www.ncbi.nlm.nih.gov/pubmed/30337987
http://dx.doi.org/10.3889/oamjms.2018.306
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author Aluloska, Natasha
Janchevska, Snezana
Tasic, Velibor
author_facet Aluloska, Natasha
Janchevska, Snezana
Tasic, Velibor
author_sort Aluloska, Natasha
collection PubMed
description BACKGROUND: Neonatal renal vein thrombosis is the most common vascular condition in the newborn kidney, which could lead to serious complication in infants. CASE REPORT: We report a case of the unilateral renal vein and inferior vena cava thrombosis, presented with gross hematuria and thrombocytopenia in a neonate. The neonate was a macrosomic male born to a mother with hyperglycemia in pregnancy. The baby was born with perinatal asphyxia and early neonatal infection and massive hematuria. Clinical and laboratory examination showed enlarged kidney having corticomedullary differentiation diminished and azotemia. Diagnosis of renal vein thrombosis was suspected by renal ultrasound and confirmed by magnetic urography. Prothrombotic risk factors were evaluated. The child is being managed conservatively. Measures aimed at the prevention of end-stage renal disease because of its poor outcome were highlighted. Despite anticoagulant therapy, the right kidney developed areas of scarring and then atrophy. CONCLUSION: In this work, we present a patient with multiple entities in the aetiology of non-catheter induced renal and vena cava thrombosis in a neonate. Clinicians should suspect renal vein thrombosis in neonates when presented with early postnatal gross hematuria, palpable abdominal mass and thrombopenia.
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spelling pubmed-61825072018-10-18 Non Catether Induced Renal and Inferior Vena Cava Trombosis in a Neonate: A Case Report Aluloska, Natasha Janchevska, Snezana Tasic, Velibor Open Access Maced J Med Sci Case Report BACKGROUND: Neonatal renal vein thrombosis is the most common vascular condition in the newborn kidney, which could lead to serious complication in infants. CASE REPORT: We report a case of the unilateral renal vein and inferior vena cava thrombosis, presented with gross hematuria and thrombocytopenia in a neonate. The neonate was a macrosomic male born to a mother with hyperglycemia in pregnancy. The baby was born with perinatal asphyxia and early neonatal infection and massive hematuria. Clinical and laboratory examination showed enlarged kidney having corticomedullary differentiation diminished and azotemia. Diagnosis of renal vein thrombosis was suspected by renal ultrasound and confirmed by magnetic urography. Prothrombotic risk factors were evaluated. The child is being managed conservatively. Measures aimed at the prevention of end-stage renal disease because of its poor outcome were highlighted. Despite anticoagulant therapy, the right kidney developed areas of scarring and then atrophy. CONCLUSION: In this work, we present a patient with multiple entities in the aetiology of non-catheter induced renal and vena cava thrombosis in a neonate. Clinicians should suspect renal vein thrombosis in neonates when presented with early postnatal gross hematuria, palpable abdominal mass and thrombopenia. Republic of Macedonia 2018-08-23 /pmc/articles/PMC6182507/ /pubmed/30337987 http://dx.doi.org/10.3889/oamjms.2018.306 Text en Copyright: © 2018 Natasha Aluloska, Snezana Janchevska, Velibor Tasic. http://creativecommons.org/licenses/CC BY-NC/4.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (CC BY-NC 4.0).
spellingShingle Case Report
Aluloska, Natasha
Janchevska, Snezana
Tasic, Velibor
Non Catether Induced Renal and Inferior Vena Cava Trombosis in a Neonate: A Case Report
title Non Catether Induced Renal and Inferior Vena Cava Trombosis in a Neonate: A Case Report
title_full Non Catether Induced Renal and Inferior Vena Cava Trombosis in a Neonate: A Case Report
title_fullStr Non Catether Induced Renal and Inferior Vena Cava Trombosis in a Neonate: A Case Report
title_full_unstemmed Non Catether Induced Renal and Inferior Vena Cava Trombosis in a Neonate: A Case Report
title_short Non Catether Induced Renal and Inferior Vena Cava Trombosis in a Neonate: A Case Report
title_sort non catether induced renal and inferior vena cava trombosis in a neonate: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6182507/
https://www.ncbi.nlm.nih.gov/pubmed/30337987
http://dx.doi.org/10.3889/oamjms.2018.306
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