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Sub-acute and long-term effects of ayahuasca on affect and cognitive thinking style and their association with ego dissolution
RATIONALE: Ayahuasca is a psychotropic plant tea from South America used for religious purposes by indigenous people of the Amazon. Increasing evidence indicates that ayahuasca may have therapeutic potential in the treatment of mental health disorders and can enhance mindfulness-related capacities....
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6182612/ https://www.ncbi.nlm.nih.gov/pubmed/30105399 http://dx.doi.org/10.1007/s00213-018-4988-3 |
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author | Uthaug, M. V. van Oorsouw, K. Kuypers, K. P. C. van Boxtel, M. Broers, N. J. Mason, N. L. Toennes, S. W. Riba, J. Ramaekers, J. G. |
author_facet | Uthaug, M. V. van Oorsouw, K. Kuypers, K. P. C. van Boxtel, M. Broers, N. J. Mason, N. L. Toennes, S. W. Riba, J. Ramaekers, J. G. |
author_sort | Uthaug, M. V. |
collection | PubMed |
description | RATIONALE: Ayahuasca is a psychotropic plant tea from South America used for religious purposes by indigenous people of the Amazon. Increasing evidence indicates that ayahuasca may have therapeutic potential in the treatment of mental health disorders and can enhance mindfulness-related capacities. Most research so far has focused on acute and sub-acute effects of ayahuasca on mental health-related parameters and less on long-term effects. OBJECTIVES: The present study aimed to assess sub-acute and long-term effects of ayahuasca on well-being and cognitive thinking style. The second objective was to assess whether sub-acute and long-term effects of ayahuasca depend on the degree of ego dissolution that was experienced after consumption of ayahuasca. RESULTS: Ayahuasca ceremony attendants (N = 57) in the Netherlands and Colombia were assessed before, the day after, and 4 weeks following the ritual. Relative to baseline, ratings of depression and stress significantly decreased after the ayahuasca ceremony and these changes persisted for 4 weeks. Likewise, convergent thinking improved post-ayahuasca ceremony up until the 4 weeks follow-up. Satisfaction with life and several aspects of mindfulness increased the day after the ceremony, but these changes failed to reach significance 4 weeks after. Changes in affect, satisfaction with life, and mindfulness were significantly correlated to the level of ego dissolution experienced during the ayahuasca ceremony and were unrelated to previous experience with ayahuasca. CONCLUSION: It is concluded that ayahuasca produces sub-acute and long-term improvements in affect and cognitive thinking style in non-pathological users. These data highlight the therapeutic potential of ayahuasca in the treatment of mental health disorders, such as depression. |
format | Online Article Text |
id | pubmed-6182612 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Springer Berlin Heidelberg |
record_format | MEDLINE/PubMed |
spelling | pubmed-61826122018-10-22 Sub-acute and long-term effects of ayahuasca on affect and cognitive thinking style and their association with ego dissolution Uthaug, M. V. van Oorsouw, K. Kuypers, K. P. C. van Boxtel, M. Broers, N. J. Mason, N. L. Toennes, S. W. Riba, J. Ramaekers, J. G. Psychopharmacology (Berl) Original Investigation RATIONALE: Ayahuasca is a psychotropic plant tea from South America used for religious purposes by indigenous people of the Amazon. Increasing evidence indicates that ayahuasca may have therapeutic potential in the treatment of mental health disorders and can enhance mindfulness-related capacities. Most research so far has focused on acute and sub-acute effects of ayahuasca on mental health-related parameters and less on long-term effects. OBJECTIVES: The present study aimed to assess sub-acute and long-term effects of ayahuasca on well-being and cognitive thinking style. The second objective was to assess whether sub-acute and long-term effects of ayahuasca depend on the degree of ego dissolution that was experienced after consumption of ayahuasca. RESULTS: Ayahuasca ceremony attendants (N = 57) in the Netherlands and Colombia were assessed before, the day after, and 4 weeks following the ritual. Relative to baseline, ratings of depression and stress significantly decreased after the ayahuasca ceremony and these changes persisted for 4 weeks. Likewise, convergent thinking improved post-ayahuasca ceremony up until the 4 weeks follow-up. Satisfaction with life and several aspects of mindfulness increased the day after the ceremony, but these changes failed to reach significance 4 weeks after. Changes in affect, satisfaction with life, and mindfulness were significantly correlated to the level of ego dissolution experienced during the ayahuasca ceremony and were unrelated to previous experience with ayahuasca. CONCLUSION: It is concluded that ayahuasca produces sub-acute and long-term improvements in affect and cognitive thinking style in non-pathological users. These data highlight the therapeutic potential of ayahuasca in the treatment of mental health disorders, such as depression. Springer Berlin Heidelberg 2018-08-13 2018 /pmc/articles/PMC6182612/ /pubmed/30105399 http://dx.doi.org/10.1007/s00213-018-4988-3 Text en © The Author(s) 2018 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. |
spellingShingle | Original Investigation Uthaug, M. V. van Oorsouw, K. Kuypers, K. P. C. van Boxtel, M. Broers, N. J. Mason, N. L. Toennes, S. W. Riba, J. Ramaekers, J. G. Sub-acute and long-term effects of ayahuasca on affect and cognitive thinking style and their association with ego dissolution |
title | Sub-acute and long-term effects of ayahuasca on affect and cognitive thinking style and their association with ego dissolution |
title_full | Sub-acute and long-term effects of ayahuasca on affect and cognitive thinking style and their association with ego dissolution |
title_fullStr | Sub-acute and long-term effects of ayahuasca on affect and cognitive thinking style and their association with ego dissolution |
title_full_unstemmed | Sub-acute and long-term effects of ayahuasca on affect and cognitive thinking style and their association with ego dissolution |
title_short | Sub-acute and long-term effects of ayahuasca on affect and cognitive thinking style and their association with ego dissolution |
title_sort | sub-acute and long-term effects of ayahuasca on affect and cognitive thinking style and their association with ego dissolution |
topic | Original Investigation |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6182612/ https://www.ncbi.nlm.nih.gov/pubmed/30105399 http://dx.doi.org/10.1007/s00213-018-4988-3 |
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