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PAXX Participates in Base Excision Repair via Interacting with Pol β and Contributes to TMZ Resistance in Glioma Cells

Non-homologous end joining (NHEJ) is one of the major DNA repair pathway in mammalian cell that can ligate a variety of DNA ends. However, how does all NHEJ factors communicate and organize together to achieve the final repair is still not clear. PAralog of XRCC4 and XLF (PAXX) was a new factor iden...

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Detalles Bibliográficos
Autores principales: Yang, Ben, Fu, Xueqi, Hao, Jilong, Sun, Jing, Li, Zongzhu, Li, Haisong, Xu, Haiyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6182633/
https://www.ncbi.nlm.nih.gov/pubmed/30238427
http://dx.doi.org/10.1007/s12031-018-1157-4