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Antagonising Wnt/β-catenin signalling ameliorates lens-capsulotomy-induced retinal degeneration in a mouse model of diabetes

AIMS/HYPOTHESIS: Cataract surgery in diabetic individuals worsens pre-existing retinopathy and triggers the development of diabetic ocular complications, although the underlying cellular and molecular pathophysiology remains elusive. We hypothesise that lens surgery may exaggerate pre-existing retin...

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Detalles Bibliográficos
Autores principales: Hombrebueno, Jose R., Ali, Imran H. A., Ma, Jian-xing, Chen, Mei, Xu, Heping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6182657/
https://www.ncbi.nlm.nih.gov/pubmed/30019207
http://dx.doi.org/10.1007/s00125-018-4682-3