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Toll-like receptor 9 negatively regulates pancreatic islet beta cell growth and function in a mouse model of type 1 diabetes
AIMS/HYPOTHESIS: Innate immune effectors interact with the environment to contribute to the pathogenesis of the autoimmune disease, type 1 diabetes. Although recent studies have suggested that innate immune Toll-like receptors (TLRs) are involved in tissue development, little is known about the role...
Autores principales: | Liu, Mengju, Peng, Jian, Tai, Ningwen, Pearson, James A., Hu, Changyun, Guo, Junhua, Hou, Lin, Zhao, Hongyu, Wong, F. Susan, Wen, Li |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6182661/ https://www.ncbi.nlm.nih.gov/pubmed/30094467 http://dx.doi.org/10.1007/s00125-018-4705-0 |
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