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Human adipose tissue-derived stromal cells act as functional pericytes in mice and suppress high-glucose-induced proinflammatory activation of bovine retinal endothelial cells

AIMS/HYPOTHESIS: The immunomodulatory capacity of adipose tissue-derived stromal cells (ASCs) is relevant for next-generation cell therapies that aim to reverse tissue dysfunction such as that caused by diabetes. Pericyte dropout from retinal capillaries underlies diabetic retinopathy and the subseq...

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Detalles Bibliográficos
Autores principales: Hajmousa, Ghazaleh, Przybyt, Ewa, Pfister, Frederick, Paredes-Juarez, Genaro A., Moganti, Kondaiah, Busch, Stephanie, Kuipers, Jeroen, Klaassen, Ingeborg, van Luyn, Marja J. A., Krenning, Guido, Hammes, Hans-Peter, Harmsen, Martin C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6182662/
https://www.ncbi.nlm.nih.gov/pubmed/30151615
http://dx.doi.org/10.1007/s00125-018-4713-0