Maternal Alcohol Consumption During Pregnancy and the Risk of Autism Spectrum Disorders in Offspring: A Retrospective Analysis of the Millennium Cohort Study

The objective of this retrospective analysis of the longitudinal Millennium Cohort Study was to examine whether maternal alcohol consumption in pregnancy (MACP) is associated with the development of childhood autism spectrum disorders (ASD). Data on MACP and ASD were obtained from parental questionn...

Descripción completa

Detalles Bibliográficos
Autores principales: Gallagher, C., McCarthy, F. P., Ryan, R. M., Khashan, A. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2018
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6182718/
https://www.ncbi.nlm.nih.gov/pubmed/29948531
http://dx.doi.org/10.1007/s10803-018-3626-6
_version_ 1783362631169474560
author Gallagher, C.
McCarthy, F. P.
Ryan, R. M.
Khashan, A. S.
author_facet Gallagher, C.
McCarthy, F. P.
Ryan, R. M.
Khashan, A. S.
author_sort Gallagher, C.
collection PubMed
description The objective of this retrospective analysis of the longitudinal Millennium Cohort Study was to examine whether maternal alcohol consumption in pregnancy (MACP) is associated with the development of childhood autism spectrum disorders (ASD). Data on MACP and ASD were obtained from parental questionnaires. There were 18,168 singleton mother–child pairs with data on MACP, and 12,595 answered the question on ASD when the children were 11 years old. No statistically significant association was found between MACP and ASD for light (OR 0.78, 95% CI 0.48–1.29), moderate (OR 0.89, 95% CI 0.35–2.27), or heavy (OR 1.54, 95% CI 0.56–4.21) MACP. Alcohol consumption during pregnancy was not associated with the risk of developing ASD in this study cohort.
format Online
Article
Text
id pubmed-6182718
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher Springer US
record_format MEDLINE/PubMed
spelling pubmed-61827182018-10-24 Maternal Alcohol Consumption During Pregnancy and the Risk of Autism Spectrum Disorders in Offspring: A Retrospective Analysis of the Millennium Cohort Study Gallagher, C. McCarthy, F. P. Ryan, R. M. Khashan, A. S. J Autism Dev Disord Original Paper The objective of this retrospective analysis of the longitudinal Millennium Cohort Study was to examine whether maternal alcohol consumption in pregnancy (MACP) is associated with the development of childhood autism spectrum disorders (ASD). Data on MACP and ASD were obtained from parental questionnaires. There were 18,168 singleton mother–child pairs with data on MACP, and 12,595 answered the question on ASD when the children were 11 years old. No statistically significant association was found between MACP and ASD for light (OR 0.78, 95% CI 0.48–1.29), moderate (OR 0.89, 95% CI 0.35–2.27), or heavy (OR 1.54, 95% CI 0.56–4.21) MACP. Alcohol consumption during pregnancy was not associated with the risk of developing ASD in this study cohort. Springer US 2018-06-13 2018 /pmc/articles/PMC6182718/ /pubmed/29948531 http://dx.doi.org/10.1007/s10803-018-3626-6 Text en © The Author(s) 2018 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
spellingShingle Original Paper
Gallagher, C.
McCarthy, F. P.
Ryan, R. M.
Khashan, A. S.
Maternal Alcohol Consumption During Pregnancy and the Risk of Autism Spectrum Disorders in Offspring: A Retrospective Analysis of the Millennium Cohort Study
title Maternal Alcohol Consumption During Pregnancy and the Risk of Autism Spectrum Disorders in Offspring: A Retrospective Analysis of the Millennium Cohort Study
title_full Maternal Alcohol Consumption During Pregnancy and the Risk of Autism Spectrum Disorders in Offspring: A Retrospective Analysis of the Millennium Cohort Study
title_fullStr Maternal Alcohol Consumption During Pregnancy and the Risk of Autism Spectrum Disorders in Offspring: A Retrospective Analysis of the Millennium Cohort Study
title_full_unstemmed Maternal Alcohol Consumption During Pregnancy and the Risk of Autism Spectrum Disorders in Offspring: A Retrospective Analysis of the Millennium Cohort Study
title_short Maternal Alcohol Consumption During Pregnancy and the Risk of Autism Spectrum Disorders in Offspring: A Retrospective Analysis of the Millennium Cohort Study
title_sort maternal alcohol consumption during pregnancy and the risk of autism spectrum disorders in offspring: a retrospective analysis of the millennium cohort study
topic Original Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6182718/
https://www.ncbi.nlm.nih.gov/pubmed/29948531
http://dx.doi.org/10.1007/s10803-018-3626-6
work_keys_str_mv AT gallagherc maternalalcoholconsumptionduringpregnancyandtheriskofautismspectrumdisordersinoffspringaretrospectiveanalysisofthemillenniumcohortstudy
AT mccarthyfp maternalalcoholconsumptionduringpregnancyandtheriskofautismspectrumdisordersinoffspringaretrospectiveanalysisofthemillenniumcohortstudy
AT ryanrm maternalalcoholconsumptionduringpregnancyandtheriskofautismspectrumdisordersinoffspringaretrospectiveanalysisofthemillenniumcohortstudy
AT khashanas maternalalcoholconsumptionduringpregnancyandtheriskofautismspectrumdisordersinoffspringaretrospectiveanalysisofthemillenniumcohortstudy

Ejemplares similares